Metabolic activation of carcinogenic 1-nitropyrene by human cytochrome P450 1B1 in Salmonella typhimurium strain expressing an O-acetyltransferase in SOS/umu assay.

Hatanaka N, Yamazaki H, Oda Y, Guengerich FP, Nakajima M, Yokoi T
Mutat Res. 2001 497 (1-2): 223-33

PMID: 11525925 · DOI:10.1016/s1383-5718(01)00254-6

MeSH Terms (16)

Acetyltransferases Aryl Hydrocarbon Hydroxylases Biotransformation Carcinogens Cytochrome P-450 CYP1B1 Cytochrome P-450 Enzyme System Escherichia coli Humans In Vitro Techniques Microsomes, Liver Mutagens NADPH-Ferrihemoprotein Reductase Pyrenes Recombinant Proteins Salmonella typhimurium SOS Response, Genetics

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