4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release.

Ji C, Amarnath V, Pietenpol JA, Marnett LJ
Chem Res Toxicol. 2001 14 (8): 1090-6

PMID: 11511183 · DOI:10.1021/tx000186f

MeSH Terms (16)

Aldehydes Apoptosis Caspase 3 Caspases Colorectal Neoplasms Cross-Linking Reagents Cytochrome c Group DNA Damage Enzyme Induction Gene Expression Regulation, Neoplastic Genes, bcl-2 Humans Lipid Peroxidation Mitochondria Proto-Oncogene Proteins c-bcl-2 Tumor Cells, Cultured

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