Publication

Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation.

Lovett BD, Lo Nigro L, Rappaport EF, Blair IA, Osheroff N, Zheng N, Megonigal MD, Williams WR, Nowell PC, Felix CA
Proc Natl Acad Sci U S A. 2001 98 (17): 9802-7

PMID: 11493704 · PMCID: PMC55533 · DOI:10.1073/pnas.171309898

MeSH Terms (35)

Antigens, Neoplasm Antineoplastic Combined Chemotherapy Protocols Catechols Child Chromosome Breakage Chromosomes, Human, Pair 4 Chromosomes, Human, Pair 11 Combined Modality Therapy Cyclophosphamide Dactinomycin DNA, Neoplasm DNA-Binding Proteins DNA Topoisomerases, Type II Etoposide Female Histone-Lysine N-Methyltransferase Humans Ifosfamide Isoenzymes Models, Genetic Molecular Sequence Data Myeloid-Lymphoid Leukemia Protein Neoplasm Proteins Neoplasms, Second Primary Nuclear Proteins Precursor Cell Lymphoblastic Leukemia-Lymphoma Proto-Oncogenes Radiotherapy, Adjuvant Recombination, Genetic Rhabdomyosarcoma, Alveolar Soft Tissue Neoplasms Transcriptional Elongation Factors Transcription Factors Translocation, Genetic Vincristine

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