Inclusion of the herpes simplex thymidine kinase gene in a replicating adenovirus does not augment antitumor efficacy.

Lambright ES, Amin K, Wiewrodt R, Force SD, Lanuti M, Propert KJ, Litzky L, Kaiser LR, Albelda SM
Gene Ther. 2001 8 (12): 946-53

PMID: 11426335 · DOI:10.1038/sj.gt.3301489

MeSH Terms (20)

Adenoviridae Analysis of Variance Animals Antiviral Agents Female Ganciclovir Genetic Therapy Genetic Vectors Injections, Intralesional Lung Neoplasms Male Mice Mice, Nude Mice, SCID Neoplasms, Experimental Neoplasm Transplantation Simplexvirus Thymidine Kinase Transduction, Genetic Virus Replication

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