Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase.

Oda Y, Aryal P, Terashita T, Gillam EM, Guengerich FP, Shimada T
Mutat Res. 2001 492 (1-2): 81-90

PMID: 11377247 · DOI:10.1016/s1383-5718(01)00154-1

MeSH Terms (16)

Acetyltransferases Amines Arylamine N-Acetyltransferase Carcinogens Cytochrome P-450 Enzyme System Dose-Response Relationship, Drug Enzyme Activation Fluorenes Heterocyclic Compounds Humans Isoenzymes Mutagenicity Tests Mutagens NADPH-Ferrihemoprotein Reductase Salmonella typhimurium Sensitivity and Specificity

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