Abortion history and breast cancer risk: results from the Shanghai Breast Cancer Study.

Sanderson M, Shu XO, Jin F, Dai Q, Wen W, Hua Y, Gao YT, Zheng W
Int J Cancer. 2001 92 (6): 899-905

PMID: 11351314 · DOI:10.1002/ijc.1263

Studies of the association between induced abortion and breast cancer risk have been inconsistent, perhaps due to underreporting of abortions. Induced abortion is a well-accepted family planning procedure in China, and women who have several induced abortions do not feel stigmatized. The authors used data from a population-based case-control study of breast cancer among women age 25-64 conducted between 1996 and 1998 in urban Shanghai to assess whether a history of and the number of induced abortions were related to breast cancer risk. In-person interviews were completed with 1,459 incident breast cancer cases ascertained through a population-based cancer registry, and 1,556 controls randomly selected from the general population in Shanghai (with respective response rates of 91% and 90%). After adjusting for confounding, there was no relation between ever having had an induced abortion and breast cancer (odds ratio [OR] = 0.9, 95% confidence interval [CI] 0.7-1.2). Women who had 3 or more induced abortions were not at increased risk of premenopausal breast cancer (OR = 0.9, 95% CI 0.6-1.4) or postmenopausal breast cancer (OR = 1.3, 95% CI 0.8-2.3). These results suggest that a history of several induced abortions has little influence on breast cancer risk in Chinese women.

Copyright 2001 Wiley-Liss, Inc.

MeSH Terms (13)

Abortion, Induced Abortion, Spontaneous Adult Age Factors Breast Neoplasms China Female Humans Lactation Menopause Middle Aged Odds Ratio Risk Factors

Connections (3)

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