Comparison of Roche MONITOR and Organon Teknika NucliSens assays to quantify human immunodeficiency virus type 1 RNA in cerebrospinal fluid.

Spearman P, Fiscus SA, Smith RM, Shepard R, Johnson B, Nicotera J, Harris VL, Clough LA, McKinsey J, Haas DW
J Clin Microbiol. 2001 39 (4): 1612-4

PMID: 11283098 · PMCID: PMC87981 · DOI:10.1128/JCM.39.4.1612-1614.2001

We compared Roche MONITOR and Organon Teknika NucliSens assays for human immunodeficiency virus type 1 (HIV-1) RNA in cerebrospinal fluid (CSF). Results of 282 assays were highly correlated (r = 0.826), with MONITOR values being 0.29 +/- 0.4 log(10) copies/ml (mean +/- standard deviation) values. Both assays can reliably quantify HIV-1 RNA in CSF.

MeSH Terms (6)

AIDS-Related Opportunistic Infections Central Nervous System Diseases HIV-1 Humans Reagent Kits, Diagnostic RNA, Viral

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