Adaptation of reovirus to growth in the presence of protease inhibitor E64 segregates with a mutation in the carboxy terminus of viral outer-capsid protein sigma3.

Ebert DH, Wetzel JD, Brumbaugh DE, Chance SR, Stobie LE, Baer GS, Dermody TS
J Virol. 2001 75 (7): 3197-206

PMID: 11238846 · PMCID: PMC114113 · DOI:10.1128/JVI.75.7.3197-3206.2001

MeSH Terms (18)

Adaptation, Physiological Animals Capsid Capsid Proteins Cathepsin D Cathepsin L Cathepsins Cysteine Endopeptidases Cysteine Proteinase Inhibitors Endopeptidases L Cells Leucine Mice Mutation Reoviridae RNA-Binding Proteins Structure-Activity Relationship Virus Assembly

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