Efficacy and safety of recombinant human activated protein C for severe sepsis.

Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ, Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group
N Engl J Med. 2001 344 (10): 699-709

PMID: 11236773 · DOI:10.1056/NEJM200103083441001

MeSH Terms (14)

Anti-Inflammatory Agents, Non-Steroidal Double-Blind Method Fibrin Fibrinogen Degradation Products Fibrinolytic Agents Hemorrhage Humans Infections Interleukin-6 Prospective Studies Protein C Recombinant Proteins Risk Survival Analysis Systemic Inflammatory Response Syndrome

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