The hepatitis B virus encoded oncoprotein pX amplifies TGF-beta family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosis.

Lee DK, Park SH, Yi Y, Choi SG, Lee C, Parks WT, Cho H, de Caestecker MP, Shaul Y, Roberts AB, Kim SJ
Genes Dev. 2001 15 (4): 455-66

PMID: 11230153 · PMCID: PMC312630 · DOI:10.1101/gad.856201

MeSH Terms (14)

3T3 Cells Animals Cell Nucleus DNA-Binding Proteins Hepatitis B virus Liver Cirrhosis Mice Oncogene Proteins, Viral Protein Binding Signal Transduction Smad4 Protein Trans-Activators Transcriptional Activation Transforming Growth Factor beta

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