Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies.

Petros AM, Nettesheim DG, Wang Y, Olejniczak ET, Meadows RP, Mack J, Swift K, Matayoshi ED, Zhang H, Thompson CB, Fesik SW
Protein Sci. 2000 9 (12): 2528-34

PMID: 11206074 · PMCID: PMC2144516 · DOI:10.1110/ps.9.12.2528

MeSH Terms (17)

Amino Acid Sequence Apoptosis bcl-Associated Death Protein bcl-X Protein Binding Sites Carrier Proteins Humans Models, Molecular Mutagenesis, Site-Directed Nuclear Magnetic Resonance, Biomolecular Peptides Protein Binding Protein Engineering Protein Structure, Secondary Protein Structure, Tertiary Proto-Oncogene Proteins c-bcl-2 Structure-Activity Relationship

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