Role of iron in Helicobacter pylori: its influence in outer membrane protein expression and in pathogenicity.

Pérez-Pérez GI, Israel DA
Eur J Gastroenterol Hepatol. 2000 12 (12): 1263-5

PMID: 11192313 · DOI:10.1097/00042737-200012120-00001

The acquisition of iron is a necessity for bacterial growth in Helicobacterpylori, as it is for other organisms. In addition, iron is a critical factor for the virulence of this organism. Therefore, it is not surprising that H. pylori isolates have the potential to express at least three major iron acquisition mechanisms. The association of H. pylori infection with host iron deficiency might indicate that the iron-scavenging systems play a role in the virulence of H. pylori.

MeSH Terms (7)

Bacterial Outer Membrane Proteins Colony Count, Microbial Helicobacter Infections Helicobacter pylori Humans Iron Sensitivity and Specificity

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