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The electron density distribution of tobacco mosaic virus has been determined to 6.7 A resolution by analysis of the X-ray diffraction pattern given by oriented gels of the virus. This has been achieved by separation of overlapping Bessel function terms by a technique analogous to crystallographic isomorphous replacement. The course of the polypeptide chain of the coat protein may be traced for a large part of its length.
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Released July 13, 2020