Publication

Structure of tobacco mosaic virus at 6.7 å resolution.

Holmes KC, Stubbs GJ, Mandelkow E, Gallwitz U
Nature. 1975 254 (5497): 192-6

PMID: 1113882 · DOI:10.1038/254192a0

The electron density distribution of tobacco mosaic virus has been determined to 6.7 A resolution by analysis of the X-ray diffraction pattern given by oriented gels of the virus. This has been achieved by separation of overlapping Bessel function terms by a technique analogous to crystallographic isomorphous replacement. The course of the polypeptide chain of the coat protein may be traced for a large part of its length.

MeSH Terms (8)

Fourier Analysis Models, Structural Nucleic Acid Conformation Protein Conformation RNA, Viral Tobacco Mosaic Virus Viral Proteins X-Ray Diffraction

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