Congeners of N(alpha)-acetyl-L-cysteine but not aminoguanidine act as neuroprotectants from the lipid peroxidation product 4-hydroxy-2-nonenal.

Neely MD, Zimmerman L, Picklo MJ, Ou JJ, Morales CR, Montine KS, Amaranth V, Montine TJ
Free Radic Biol Med. 2000 29 (10): 1028-36

PMID: 11084291 · DOI:10.1016/s0891-5849(00)00411-1

MeSH Terms (15)

Acetylcysteine Aldehydes Animals Brain Cell Line Free Radical Scavengers Guanidines In Vitro Techniques Lipid Peroxidation Magnetic Resonance Spectroscopy Male Mitochondria Neuroprotective Agents Rats Rats, Sprague-Dawley

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