Streptokinase binds preferentially to the extended conformation of plasminogen through lysine binding site and catalytic domain interactions.

Boxrud PD, Bock PE
Biochemistry. 2000 39 (45): 13974-81

PMID: 11076540 · DOI:10.1021/bi000594i

MeSH Terms (13)

Amino Acid Chloromethyl Ketones Aminocaproic Acid Binding Sites Catalytic Domain Chlorides Fibrinolysin Glutamic Acid Humans Lysine Plasminogen Protein Conformation Serine Proteinase Inhibitors Streptokinase

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