Alanine scanning mutants of rat proinsulin I show functional diversity of anti-insulin monoclonal antibodies.

Tikhomirov OY, Thomas JW
J Immunol. 2000 165 (7): 3876-82

PMID: 11034394 · DOI:10.4049/jimmunol.165.7.3876

MeSH Terms (16)

Alanine Amino Acid Substitution Animals Antibodies, Monoclonal Antibody Affinity Antigen-Antibody Reactions Humans Mice Mice, Inbred BALB C Models, Molecular Mutagenesis, Site-Directed Proinsulin Rats Recombinant Fusion Proteins Recombinant Proteins Swine

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