Bacterial vaginosis and cervical dilation and effacement at 24-29 weeks' gestation.

Pastore LM, Hartmann KE, Thorp JM, Royce RA, Jackson TP, Savitz DA
Am J Perinatol. 2000 17 (2): 83-8

PMID: 11023166 · DOI:10.1055/s-2000-9275

The purpose of this study was to investigate the association between bacterial vaginosis (BV) and cervical dilation and effacement, as measures of impending preterm delivery. The Pregnancy, Infection, and Nutrition Study collected genital tract specimens and documented cervical change from 807 eligible women between 24 and 29 weeks' gestation. BV was assessed with Nugent-scored vaginal smears, and analyzed in relation to cervical measurements. At 24-29 weeks' gestation, <7% of women had a dilated cervix, 31% had a cervix < or =2 cm, and 17.3% had BV. Unadjusted analyses found no associations between BV and cervical measurements. Adjusted logistic regression suggested an association between BV and cervical effacement among women with a sexually transmitted disease (STD) earlier in pregnancy (odds ratio = 1.9, 95% CI 0.8-4.3). Stratified analyses for BV/dilation also suggested interaction with STDs. Overall, BV was not association with cervical dilation or effacement at 24-29 weeks' gestation.

MeSH Terms (9)

Cervix Uteri Female Humans Obstetric Labor, Premature Pregnancy Pregnancy Complications, Infectious Pregnancy Trimester, Third Risk Factors Vaginosis, Bacterial

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