Rate-determining steps in phenacetin oxidations by human cytochrome P450 1A2 and selected mutants.

Yun CH, Miller GP, Guengerich FP
Biochemistry. 2000 39 (37): 11319-29

PMID: 10985777 · DOI:10.1021/bi000869u

MeSH Terms (16)

Binding Sites Catalysis Chromatography, High Pressure Liquid Cytochrome P-450 CYP1A2 Deuterium Enzyme Activation Ferric Compounds Humans Hydrogen Peroxide Kinetics Mutagenesis, Site-Directed NADP Oxidation-Reduction Phenacetin Recombinant Proteins tert-Butylhydroperoxide

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