The live attenuated subgroup B respiratory syncytial virus vaccine candidate RSV 2B33F is attenuated and immunogenic in chimpanzees, but exhibits partial loss of the ts phenotype following replication in vivo.

Crowe JE, Randolph V, Murphy BR
Virus Res. 1999 59 (1): 13-22

PMID: 10854162 · DOI:10.1016/s0168-1702(98)00118-x

MeSH Terms (13)

Animals Female Male Mutation Pan troglodytes Phenotype Respiratory Syncytial Virus, Human Respiratory Syncytial Virus Infections Temperature Vaccines, Attenuated Viral Plaque Assay Viral Vaccines Virus Replication

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