Publication

Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma.

Bruns CJ, Solorzano CC, Harbison MT, Ozawa S, Tsan R, Fan D, Abbruzzese J, Traxler P, Buchdunger E, Radinsky R, Fidler IJ
Cancer Res. 2000 60 (11): 2926-35

PMID: 10850439

MeSH Terms (25)

Administration, Oral Animals Antineoplastic Combined Chemotherapy Protocols Apoptosis Blotting, Western Deoxycytidine Down-Regulation Endothelium ErbB Receptors Fluorescent Antibody Technique Humans Immunohistochemistry In Situ Nick-End Labeling Male Mice Mice, Nude Neoplasm Transplantation Pancreatic Neoplasms Platelet Endothelial Cell Adhesion Molecule-1 Protein-Tyrosine Kinases Pyrimidines Pyrroles Signal Transduction Time Factors Tumor Cells, Cultured

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