Streptokinase binds to human plasmin with high affinity, perturbs the plasmin active site, and induces expression of a substrate recognition exosite for plasminogen.

Boxrud PD, Fay WP, Bock PE
J Biol Chem. 2000 275 (19): 14579-89

PMID: 10799544 · DOI:10.1074/jbc.275.19.14579

MeSH Terms (13)

Animals Binding Sites Cattle Fibrinolysin Fluorescent Dyes Humans Hydrolysis Kinetics Plasminogen Recombinant Proteins Spectrometry, Fluorescence Streptokinase Substrate Specificity

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