Sensitivity of human type II topoisomerases to DNA damage: stimulation of enzyme-mediated DNA cleavage by abasic, oxidized and alkylated lesions.

Sabourin M, Osheroff N
Nucleic Acids Res. 2000 28 (9): 1947-54

PMID: 10756196 · PMCID: PMC103304 · DOI:10.1093/nar/28.9.1947

MeSH Terms (18)

Adenine Alkylation Apurinic Acid Base Sequence DNA DNA-Binding Proteins DNA Adducts DNA Damage DNA Repair DNA Topoisomerases, Type II Guanine Humans Isoenzymes Mutation Oligonucleotides Oxidation-Reduction Plasmids Sensitivity and Specificity

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