TCDD induces CYP1A4 and CYP1A5 in chick liver and kidney and only CYP1A4, an enzyme lacking arachidonic acid epoxygenase activity, in myocardium and vascular endothelium.

Gannon M, Gilday D, Rifkind AB
Toxicol Appl Pharmacol. 2000 164 (1): 24-37

PMID: 10739741 · DOI:10.1006/taap.1999.8864

MeSH Terms (15)

Animals Arachidonic Acid Aryl Hydrocarbon Hydroxylases Chick Embryo Cytochrome P-450 CYP1A1 Cytochrome P-450 Enzyme System Endothelium, Vascular Enzyme Induction Heart Intestines Kidney Liver Organ Specificity Oxidoreductases Polychlorinated Dibenzodioxins

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