Inhibition of the 26S proteasome induces expression of GLCLC, the catalytic subunit for gamma-glutamylcysteine synthetase.

Sekhar KR, Soltaninassab SR, Borrelli MJ, Xu ZQ, Meredith MJ, Domann FE, Freeman ML
Biochem Biophys Res Commun. 2000 270 (1): 311-7

PMID: 10733945 · DOI:10.1006/bbrc.2000.2419

MeSH Terms (15)

Acetylcysteine Azetidines Cells, Cultured DNA-Binding Proteins Enzyme Induction Glutamate-Cysteine Ligase Glutathione Liver Neoplasm Proteins NF-E2-Related Factor 2 Peptide Hydrolases Proteasome Endopeptidase Complex Protein Structure, Quaternary Response Elements Trans-Activators

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