Farnesyltransferase inhibitor-induced regression of mammary tumors in TGF alpha and TGF alpha/neu transgenic mice correlates with inhibition of map kinase and p70s6 kinase phosphorylation.

Nørgaard P, Law BK, Plovisson HS, Moses HL
Ann N Y Acad Sci. 1999 886: 265-8

PMID: 10667235 · DOI:10.1111/j.1749-6632.1999.tb09432.x

MeSH Terms (13)

Alkyl and Aryl Transferases Animals Antineoplastic Agents Enzyme Inhibitors Farnesyltranstransferase Genes, erbB-2 Mammary Neoplasms, Experimental Mice Mice, Transgenic Mitogen-Activated Protein Kinases Phosphorylation Ribosomal Protein S6 Kinases Transforming Growth Factors

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