Forty years of PRCs--what have we learned?

Johnson CH
Chronobiol Int. 1999 16 (6): 711-43

PMID: 10584173 · DOI:10.3109/07420529909016940

What are phase-response curves (PRCs)? How can they be measured? How should they be plotted? These questions and many other fascinating facets of PRCs are addressed in this review, including research topics in which phase-resetting data have provided crucial insights: entrainment, phototransduction, pacemaker mechanism, phase markers of the pacemaker, and gauges of oscillator amplitude. PRCs have enlightened us and will continue to be a valuable tool in clock research.

MeSH Terms (5)

Activity Cycles Animals Biological Clocks Circadian Rhythm Humans

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