Biphenotypic B/macrophage cells express COX-1 and up-regulate COX-2 expression and prostaglandin E(2) production in response to pro-inflammatory signals.

Graf BA, Nazarenko DA, Borrello MA, Roberts LJ, Morrow JD, Palis J, Phipps RP
Eur J Immunol. 1999 29 (11): 3793-803

PMID: 10556836 · DOI:10.1002/(SICI)1521-4141(199911)29:11<3793::AID-IMMU3793>3.0.CO;2-3

MeSH Terms (21)

Animals B-Lymphocytes Blotting, Western Cells, Cultured Cyclooxygenase 1 Cyclooxygenase 2 Dinoprost Dinoprostone Gene Expression Regulation, Enzymologic Immunohistochemistry Immunophenotyping Isoenzymes Macrophages Membrane Proteins Mice Prostaglandin-Endoperoxide Synthases Prostaglandin D2 Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger Signal Transduction Up-Regulation

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