Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis.

Davis EA, Cuesta-Muñoz A, Raoul M, Buettger C, Sweet I, Moates M, Magnuson MA, Matschinsky FM
Diabetologia. 1999 42 (10): 1175-86

PMID: 10525657 · DOI:10.1007/s001250051289

MeSH Terms (19)

Adaptor Proteins, Signal Transducing Adenosine Triphosphate Blood Glucose Carrier Proteins Enzyme Activation Enzyme Stability Glucokinase Glucose Glutathione Transferase Homeostasis Humans Hyperglycemia Hypoglycemia Insulin Models, Biological Mutation Proteins Recombinant Fusion Proteins Syndrome

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