Novel inhibitors of Erm methyltransferases from NMR and parallel synthesis.

Hajduk PJ, Dinges J, Schkeryantz JM, Janowick D, Kaminski M, Tufano M, Augeri DJ, Petros A, Nienaber V, Zhong P, Hammond R, Coen M, Beutel B, Katz L, Fesik SW
J Med Chem. 1999 42 (19): 3852-9

PMID: 10508434 · DOI:10.1021/jm990293a

MeSH Terms (13)

Binding Sites Crystallography, X-Ray Drug Design Drug Resistance, Microbial Ligands Magnetic Resonance Spectroscopy Methyltransferases Models, Chemical Models, Molecular Protein Conformation S-Adenosylmethionine Structure-Activity Relationship Triazines

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