Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense.

Wilson CL, Ouellette AJ, Satchell DP, Ayabe T, López-Boado YS, Stratman JL, Hultgren SJ, Matrisian LM, Parks WC
Science. 1999 286 (5437): 113-7

PMID: 10506557 · DOI:10.1126/science.286.5437.113

MeSH Terms (22)

Amino Acid Sequence Animals Catalysis Cytoplasmic Granules Escherichia coli Escherichia coli Infections Female Humans Immunity, Innate Immunity, Mucosal Intestinal Mucosa Intestine, Small Male Matrix Metalloproteinase 7 Metalloendopeptidases Mice Molecular Sequence Data Paneth Cells Protein Precursors Recombinant Fusion Proteins Salmonella typhimurium Tissue Extracts

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