An overlapping subzone technique for MR-based elastic property reconstruction.

Van Houten EE, Paulsen KD, Miga MI, Kennedy FE, Weaver JB
Magn Reson Med. 1999 42 (4): 779-86

PMID: 10502768 · DOI:10.1002/(sici)1522-2594(199910)42:4<779::aid-mrm21>;2-z

A finite element-based nonlinear inversion scheme for magnetic resonance (MR) elastography is detailed. The algorithm operates on small overlapping subzones of the total region of interest, processed in a hierarchical order as determined by progressive error minimization. This zoned approach allows for a high degree of spatial discretization, taking advantage of the data-rich environment afforded by the MR. The inversion technique is tested in simulation under high-noise conditions (15% random noise applied to the displacement data) with both complicated user-defined stiffness distributions and realistic tissue geometries obtained by thresholding MR image slices. In both cases the process has proved successful and has been capable of discerning small inclusions near 4 mm in diameter. Magn Reson Med 42:779-786, 1999.

Copyright 1999 Wiley-Liss, Inc.

MeSH Terms (10)

Algorithms Brain Breast Elasticity Female Finite Element Analysis Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Male

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