Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs.

Barlow C, Dennery PA, Shigenaga MK, Smith MA, Morrow JD, Roberts LJ, Wynshaw-Boris A, Levine RL
Proc Natl Acad Sci U S A. 1999 96 (17): 9915-9

PMID: 10449794 · PMCID: PMC22310 · DOI:10.1073/pnas.96.17.9915

MeSH Terms (18)

Animals Ataxia Telangiectasia Ataxia Telangiectasia Mutated Proteins Cell Cycle Proteins DNA-Binding Proteins Heme Oxygenase (Decyclizing) Heme Oxygenase-1 Isoenzymes Lipid Metabolism Membrane Proteins Mice Mice, Knockout Oxidation-Reduction Oxidative Stress Protein-Serine-Threonine Kinases Proteins Purkinje Cells Tumor Suppressor Proteins

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