The binding of arachidonic acid in the cyclooxygenase active site of mouse prostaglandin endoperoxide synthase-2 (COX-2). A putative L-shaped binding conformation utilizing the top channel region.

Rowlinson SW, Crews BC, Lanzo CA, Marnett LJ
J Biol Chem. 1999 274 (33): 23305-10

PMID: 10438506 · DOI:10.1074/jbc.274.33.23305

MeSH Terms (11)

Animals Arachidonic Acid Binding Sites Cyclooxygenase 2 Isoenzymes Mice Models, Molecular Mutagenesis, Site-Directed Prostaglandin-Endoperoxide Synthases Protein Conformation Sheep

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