Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice.

Cyrus T, Witztum JL, Rader DJ, Tangirala R, Fazio S, Linton MF, Funk CD
J Clin Invest. 1999 103 (11): 1597-604

PMID: 10359569 · PMCID: PMC408369 · DOI:10.1172/JCI5897

MeSH Terms (14)

Animals Aorta Apolipoproteins E Arachidonate 12-Lipoxygenase Arachidonate 15-Lipoxygenase Arteriosclerosis Autoantibodies Female Lipid Metabolism Lipoproteins, LDL Male Mice Mice, Inbred C57BL Mice, Knockout

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