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Results: 881 to 882 of 882

Publication Record


Autoradiographic and electron microscopic studies of minced cardiac muscle regeneration in the adult newt, notophthalmus viridescens.
Bader D, Oberpriller J
(1979) J Exp Zool 208: 177-93
MeSH Terms: Animals, Cell Differentiation, Cell Division, Heart, Myocardium, Regeneration, Salamandridae, Time Factors, Urodela
Show Abstract · Added September 28, 2015
The regenerative response of minced cardiac muscle grafts in the adult newt was studied using autoradiography and electron microscopy. One-sixteenth to one-eighth of the newt ventricle was amputated, minced, and returned to the wounded ventricle. At five days after grafting, no reorganization of graft msucle pieces was apparent and there was degeneration of much of the muscle graft. Another, smaller population of 5-day myocytes had euchromatic nuclei and intact sarcolemmae. In 10- and 16-day grafts, continuity between ventricular and graft lumina was established and coalescence of graft pieces was apparent. Ultrastructurally, 10- and 16-day graft myocytes appeared to have fewer myofibrillae and increased amounts of rough endoplasmic reticulum, polyribosomes, Golig complexes, and dense bodies when compared to uninjured ventricular myocytes. The peak of proliferative activity of graft cells was observed at 16 days. Electron microscopic autoradiography revealed breadkdown of myofibrillar structure in labeled myocytes, whereas in myocytes in the later stages of mitosis only scattered myofilaments and no Z bands were present. By 30 days, grafts appeared as an integrated structure composed primarily of cardiac muscle. Myocytes of 30-day grafts were observed in various stages of myofibrillogenesis and contained numberous 10-nm filaments. Seventy-day graft mycoytes had numberous well organized myofibrillae and intercellular junctions similar to those seen in uninjured ventricular myocytes.
1 Communities
1 Members
0 Resources
9 MeSH Terms
Lack of DR antigens on human B-lymphocyte-mouse fibroblast hybrids that express HLA-A,B antigens.
Glassy MC, Pellegrino MA, Quaranta V, Molinaro GA, Ferrone S
(1979) Transplant Proc 11: 1719-21
MeSH Terms: Animals, B-Lymphocytes, Cell Differentiation, Cell Line, Chromosomes, Human, 6-12 and X, Clone Cells, Epitopes, Fibroblasts, HLA Antigens, Humans, Hybrid Cells, Mice, Polymorphism, Genetic, Rabbits
Added March 27, 2014
1 Communities
1 Members
0 Resources
14 MeSH Terms