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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 71 to 79 of 79

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B-RAF inhibitors: an evolving role in the therapy of malignant melanoma.
Shepherd C, Puzanov I, Sosman JA
(2010) Curr Oncol Rep 12: 146-52
MeSH Terms: Antineoplastic Agents, Humans, Melanoma, Proto-Oncogene Proteins B-raf
Added March 5, 2014
0 Communities
2 Members
0 Resources
4 MeSH Terms
Inside life of melanoma cell signaling, molecular insights, and therapeutic targets.
Sosman JA, Margolin KA
(2009) Curr Oncol Rep 11: 405-11
MeSH Terms: Antineoplastic Agents, Humans, Melanoma, Models, Biological, Mutation, PTEN Phosphohydrolase, Protein Kinases, Proto-Oncogene Proteins B-raf, Proto-Oncogene Proteins c-akt, Signal Transduction, TOR Serine-Threonine Kinases
Added March 5, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Genetic predictors of MEK dependence in non-small cell lung cancer.
Pratilas CA, Hanrahan AJ, Halilovic E, Persaud Y, Soh J, Chitale D, Shigematsu H, Yamamoto H, Sawai A, Janakiraman M, Taylor BS, Pao W, Toyooka S, Ladanyi M, Gazdar A, Rosen N, Solit DB
(2008) Cancer Res 68: 9375-83
MeSH Terms: Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, ErbB Receptors, Extracellular Signal-Regulated MAP Kinases, Female, Humans, Lung Neoplasms, MAP Kinase Signaling System, Male, Mutation, Proto-Oncogene Proteins, Proto-Oncogene Proteins B-raf, Proto-Oncogene Proteins p21(ras), ras Proteins
Added March 24, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
CpG island methylator phenotype associates with low-degree chromosomal abnormalities in colorectal cancer.
Cheng YW, Pincas H, Bacolod MD, Schemmann G, Giardina SF, Huang J, Barral S, Idrees K, Khan SA, Zeng Z, Rosenberg S, Notterman DA, Ott J, Paty P, Barany F
(2008) Clin Cancer Res 14: 6005-13
MeSH Terms: Chromosomal Instability, Chromosome Aberrations, Colorectal Neoplasms, CpG Islands, DNA Methylation, Epigenesis, Genetic, Female, Gene Expression Regulation, Neoplastic, Genome, Human, Humans, Male, Microsatellite Repeats, Mutation, Phenotype, Proto-Oncogene Proteins B-raf
Added March 28, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Oxidative stress plays a critical role in inactivating mutant BRAF by geldanamycin derivatives.
Fukuyo Y, Inoue M, Nakajima T, Higashikubo R, Horikoshi NT, Hunt C, Usheva A, Freeman ML, Horikoshi N
(2008) Cancer Res 68: 6324-30
MeSH Terms: Acetylcysteine, Antibiotics, Antineoplastic, Benzoquinones, Cell Line, Tumor, Enzyme Activation, HSP90 Heat-Shock Proteins, Humans, Lactams, Macrocyclic, Mitogen-Activated Protein Kinases, Mutation, Oxidative Stress, Proto-Oncogene Proteins B-raf
Added March 5, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Constitutive activation of Raf-1 induces glioma formation in mice.
Lyustikman Y, Momota H, Pao W, Holland EC
(2008) Neoplasia 10: 501-10
MeSH Terms: Animals, Animals, Newborn, Blotting, Western, Brain, Brain Neoplasms, Cyclin-Dependent Kinase Inhibitor p16, Genes, ras, Glioblastoma, Humans, Immunoenzyme Techniques, Mice, Mice, Knockout, Mutation, Proto-Oncogene Proteins B-raf, Proto-Oncogene Proteins c-akt, Proto-Oncogene Proteins c-raf
Added March 24, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
B-Raf-mediated signaling pathway regulates T cell development.
Tsukamoto H, Irie A, Senju S, Hatzopoulos AK, Wojnowski L, Nishimura Y
(2008) Eur J Immunol 38: 518-27
MeSH Terms: Animals, Cell Differentiation, Cells, Cultured, Coculture Techniques, Enzyme Induction, Extracellular Signal-Regulated MAP Kinases, Humans, Jurkat Cells, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Mice, Knockout, Proto-Oncogene Proteins B-raf, Retrospective Studies, Signal Transduction, T-Lymphocytes, Thymus Gland
Added November 18, 2010
1 Communities
1 Members
0 Resources
17 MeSH Terms
Rafs constitute a nodal point in the regulation of embryonic endothelial progenitor cell growth and differentiation.
Bidzhekov K, Hautmann M, Semisch M, Weber C, Engelmann B, Hatzopoulos AK
(2007) J Cell Mol Med 11: 1395-407
MeSH Terms: Animals, Cell Differentiation, Cell Proliferation, Cell Separation, Cloning, Molecular, Embryo, Mammalian, Endothelial Cells, Enzyme Activation, Estrogens, Genetic Engineering, Mice, Models, Biological, Phosphorylation, Protein Structure, Tertiary, Proto-Oncogene Proteins B-raf, Proto-Oncogene Proteins c-raf, RNA Interference, Receptors, Estrogen, Recombinant Fusion Proteins, Stem Cells
Added November 18, 2010
1 Communities
1 Members
0 Resources
20 MeSH Terms
Rap1 couples cAMP signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory.
Morozov A, Muzzio IA, Bourtchouladze R, Van-Strien N, Lapidus K, Yin D, Winder DG, Adams JP, Sweatt JD, Kandel ER
(2003) Neuron 39: 309-25
MeSH Terms: Animals, Antirheumatic Agents, Bacterial Proteins, Behavior, Animal, Blotting, Western, Colforsin, Conditioning, Psychological, Cues, Cyclic AMP, Electric Stimulation, Electrophysiology, Excitatory Postsynaptic Potentials, Gene Expression Regulation, Enzymologic, Hippocampus, Immunoenzyme Techniques, In Situ Hybridization, Interleukin 1 Receptor Antagonist Protein, Long-Term Potentiation, Memory, Metalloproteins, Mice, Mice, Transgenic, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Mitogen-Activated Protein Kinases, Mutation, Neuronal Plasticity, Prosencephalon, Proto-Oncogene Proteins B-raf, Proto-Oncogene Proteins c-raf, RNA, Messenger, Reaction Time, Sialoglycoproteins, Signal Transduction, Subcellular Fractions, Synapses, Synaptic Transmission, Tetanus, Theta Rhythm, Valine, rap1 GTP-Binding Proteins
Added May 19, 2014
0 Communities
1 Members
0 Resources
41 MeSH Terms