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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 51 to 60 of 60

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Identifying QT prolongation from ECG impressions using natural language processing and negation detection.
Denny JC, Peterson JF
(2007) Stud Health Technol Inform 129: 1283-8
MeSH Terms: Algorithms, Electrocardiography, Humans, Long QT Syndrome, Natural Language Processing, Unified Medical Language System
Added May 27, 2014
0 Communities
1 Members
0 Resources
6 MeSH Terms
Preparation, functional characterization, and NMR studies of human KCNE1, a voltage-gated potassium channel accessory subunit associated with deafness and long QT syndrome.
Tian C, Vanoye CG, Kang C, Welch RC, Kim HJ, George AL, Sanders CR
(2007) Biochemistry 46: 11459-72
MeSH Terms: Amino Acid Sequence, Animals, Arrhythmias, Cardiac, Cloning, Molecular, Deafness, Escherichia coli, Female, Humans, KCNQ1 Potassium Channel, Long QT Syndrome, Magnetic Resonance Spectroscopy, Models, Molecular, Molecular Sequence Data, Oocytes, Polymerase Chain Reaction, Potassium Channels, Voltage-Gated, Protein Structure, Secondary, Recombinant Proteins, Solutions, Xenopus
Added November 21, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Genetic susceptibility to acquired long QT syndrome: pharmacologic challenge in first-degree relatives.
Kannankeril PJ, Roden DM, Norris KJ, Whalen SP, George AL, Murray KT
(2005) Heart Rhythm 2: 134-40
MeSH Terms: Anti-Arrhythmia Agents, Electrocardiography, Female, Genetic Predisposition to Disease, Humans, Long QT Syndrome, Male, Middle Aged, Quinidine
Added January 20, 2015
0 Communities
1 Members
0 Resources
9 MeSH Terms
Cross-sectional relations of electrocardiographic QRS duration to left ventricular dimensions: the Framingham Heart Study.
Dhingra R, Ho Nam B, Benjamin EJ, Wang TJ, Larson MG, D'Agostino RB, Levy D, Vasan RS
(2005) J Am Coll Cardiol 45: 685-9
MeSH Terms: Adult, Aged, Bundle-Branch Block, Cardiac Volume, Cohort Studies, Echocardiography, Electrocardiography, Female, Humans, Hypertrophy, Left Ventricular, Linear Models, Long QT Syndrome, Male, Mathematical Computing, Middle Aged, Myocardial Contraction, Signal Processing, Computer-Assisted, Statistics as Topic, Ventricular Dysfunction, Left, Ventricular Remodeling
Added April 15, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
A structural requirement for processing the cardiac K+ channel KCNQ1.
Kanki H, Kupershmidt S, Yang T, Wells S, Roden DM
(2004) J Biol Chem 279: 33976-83
MeSH Terms: Alanine, Algorithms, Amino Acid Sequence, Bacterial Proteins, Dimerization, Electric Conductivity, Electrophoresis, Polyacrylamide Gel, Epitopes, Fluorescent Dyes, Gene Deletion, Immunohistochemistry, Immunosorbent Techniques, KCNQ Potassium Channels, KCNQ1 Potassium Channel, Leucine Zippers, Long QT Syndrome, Luminescent Proteins, Mutagenesis, Site-Directed, Mutation, Patch-Clamp Techniques, Peptide Fragments, Polymerase Chain Reaction, Potassium Channels, Potassium Channels, Voltage-Gated, Protein Structure, Secondary, Recombinant Fusion Proteins, Structure-Activity Relationship, Transfection
Added January 17, 2014
0 Communities
1 Members
0 Resources
28 MeSH Terms
Cardiac-enriched LIM domain protein fhl2 is required to generate I(Ks) in a heterologous system.
Kupershmidt S, Yang IC, Sutherland M, Wells KS, Yang T, Yang P, Balser JR, Roden DM
(2002) Cardiovasc Res 56: 93-103
MeSH Terms: Animals, CHO Cells, Cell Membrane, Cricetinae, Genetic Engineering, Homeodomain Proteins, Immunohistochemistry, KCNQ Potassium Channels, KCNQ1 Potassium Channel, Long QT Syndrome, Oligonucleotides, Antisense, Patch-Clamp Techniques, Potassium Channels, Potassium Channels, Voltage-Gated, Transcription Factors, Transfection, Two-Hybrid System Techniques
Added January 17, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes.
Yang P, Kanki H, Drolet B, Yang T, Wei J, Viswanathan PC, Hohnloser SH, Shimizu W, Schwartz PJ, Stanton M, Murray KT, Norris K, George AL, Roden DM
(2002) Circulation 105: 1943-8
MeSH Terms: Alleles, Animals, Anti-Arrhythmia Agents, CHO Cells, Cation Transport Proteins, Cell Line, Cricetinae, DNA-Binding Proteins, ERG1 Potassium Channel, Electric Conductivity, Ether-A-Go-Go Potassium Channels, Female, Gene Frequency, Genetic Predisposition to Disease, Genetic Variation, Humans, KCNQ Potassium Channels, KCNQ1 Potassium Channel, Long QT Syndrome, Male, Mutation, NAV1.5 Voltage-Gated Sodium Channel, Polymorphism, Genetic, Potassium Channels, Potassium Channels, Voltage-Gated, Sodium Channels, Torsades de Pointes, Trans-Activators, Transcriptional Regulator ERG
Added January 20, 2015
0 Communities
1 Members
0 Resources
29 MeSH Terms
Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice.
Lee MP, Ravenel JD, Hu RJ, Lustig LR, Tomaselli G, Berger RD, Brandenburg SA, Litzi TJ, Bunton TE, Limb C, Francis H, Gorelikow M, Gu H, Washington K, Argani P, Goldenring JR, Coffey RJ, Feinberg AP
(2000) J Clin Invest 106: 1447-55
MeSH Terms: Animals, Brain Stem, Cochlea, Deafness, Disease Models, Animal, Ear, Inner, Electrocardiography, Evoked Potentials, Auditory, Brain Stem, Female, Histocytochemistry, Humans, Hyperplasia, KCNQ Potassium Channels, KCNQ1 Potassium Channel, Locomotion, Long QT Syndrome, Male, Mice, Mice, Knockout, Mutation, Organ Size, Phenotype, Potassium Channels, Potassium Channels, Voltage-Gated, Stomach
Added April 12, 2016
0 Communities
1 Members
0 Resources
25 MeSH Terms
A common polymorphism associated with antibiotic-induced cardiac arrhythmia.
Sesti F, Abbott GW, Wei J, Murray KT, Saksena S, Schwartz PJ, Priori SG, Roden DM, George AL, Goldstein SA
(2000) Proc Natl Acad Sci U S A 97: 10613-8
MeSH Terms: Amino Acid Sequence, Animals, Base Sequence, CHO Cells, Cricetinae, DNA Primers, Female, Humans, Long QT Syndrome, Male, Middle Aged, Molecular Sequence Data, Mutagenesis, Mutation, Missense, Polymorphism, Single Nucleotide, Potassium Channels, Potassium Channels, Voltage-Gated, Sulfamethoxazole
Added January 20, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system.
Kupershmidt S, Yang T, Anderson ME, Wessels A, Niswender KD, Magnuson MA, Roden DM
(1999) Circ Res 84: 146-52
MeSH Terms: Animals, Animals, Newborn, Cardiotonic Agents, Electrocardiography, Gene Expression Regulation, Developmental, Gene Targeting, Heart Conduction System, Isoproterenol, Lac Operon, Long QT Syndrome, Mice, Mice, Knockout, Potassium Channels, Potassium Channels, Voltage-Gated, Recombination, Genetic, Staining and Labeling, beta-Galactosidase
Added February 23, 2011
2 Communities
2 Members
0 Resources
17 MeSH Terms