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Results: 41 to 47 of 47

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Threonine 180 is required for G-protein-coupled receptor kinase 3- and beta-arrestin 2-mediated desensitization of the mu-opioid receptor in Xenopus oocytes.
Celver JP, Lowe J, Kovoor A, Gurevich VV, Chavkin C
(2001) J Biol Chem 276: 4894-900
MeSH Terms: Animals, Arrestins, Dose-Response Relationship, Drug, Down-Regulation, Enkephalin, Ala(2)-MePhe(4)-Gly(5)-, G Protein-Coupled Inwardly-Rectifying Potassium Channels, G-Protein-Coupled Receptor Kinase 3, Mutagenesis, Site-Directed, Oocytes, Phosphothreonine, Potassium Channels, Potassium Channels, Inwardly Rectifying, Protein Serine-Threonine Kinases, Receptors, Opioid, mu, Transfection, Xenopus, beta-Arrestins
Added December 10, 2013
0 Communities
1 Members
0 Resources
17 MeSH Terms
Molecular events associated with the regulation of signaling by M2 muscarinic receptors.
Hosey MM, Pals-Rylaarsdam R, Lee KB, Roseberry AG, Benovic JL, Gurevich VV, B√ľnemann M
(1999) Life Sci 64: 363-8
MeSH Terms: Adenylate Cyclase Toxin, Amino Acid Substitution, Arrestins, Barium, Carbachol, Cell Line, Cyclic AMP-Dependent Protein Kinases, Down-Regulation, G Protein-Coupled Inwardly-Rectifying Potassium Channels, GTP-Binding Proteins, GTPase-Activating Proteins, Genes, Dominant, Humans, Phosphorylation, Potassium Channel Blockers, Potassium Channels, Potassium Channels, Inwardly Rectifying, Proteins, RGS Proteins, Receptor, Muscarinic M2, Receptors, Muscarinic, Signal Transduction, Transfection, Virulence Factors, Bordetella, beta-Adrenergic Receptor Kinases
Added December 10, 2013
0 Communities
1 Members
0 Resources
25 MeSH Terms
Molecular basis for interactions of G protein betagamma subunits with effectors.
Ford CE, Skiba NP, Bae H, Daaka Y, Reuveny E, Shekter LR, Rosal R, Weng G, Yang CS, Iyengar R, Miller RJ, Jan LY, Lefkowitz RJ, Hamm HE
(1998) Science 280: 1271-4
MeSH Terms: Adenosine Diphosphate Ribose, Adenylyl Cyclases, Binding Sites, Calcium Channels, Cell Line, Cyclic AMP-Dependent Protein Kinases, G Protein-Coupled Inwardly-Rectifying Potassium Channels, GTP-Binding Proteins, Guanosine Diphosphate, Heterotrimeric GTP-Binding Proteins, Humans, Isoenzymes, Models, Molecular, Mutation, Phospholipase C beta, Potassium Channels, Potassium Channels, Inwardly Rectifying, Protein Conformation, Rhodopsin, Signal Transduction, Transducin, Type C Phospholipases, beta-Adrenergic Receptor Kinases
Added December 10, 2013
0 Communities
1 Members
0 Resources
23 MeSH Terms
RGS4 inhibits signaling by group I metabotropic glutamate receptors.
Saugstad JA, Marino MJ, Folk JA, Hepler JR, Conn PJ
(1998) J Neurosci 18: 905-13
MeSH Terms: Age Factors, Animals, Calcium, Calcium Channels, Calcium-Calmodulin-Dependent Protein Kinases, Cell Membrane, Chloride Channels, G Protein-Coupled Inwardly-Rectifying Potassium Channels, GTP-Binding Proteins, Glioma, Hippocampus, Hybrid Cells, Inositol 1,4,5-Trisphosphate, Isoenzymes, Mice, Neurons, Oocytes, Patch-Clamp Techniques, Phospholipase C beta, Potassium Channels, Potassium Channels, Inwardly Rectifying, Proteins, RGS Proteins, RNA, Messenger, Rats, Receptors, Metabotropic Glutamate, Receptors, Muscarinic, Signal Transduction, Synapses, Tritium, Type C Phospholipases, Xenopus
Added February 19, 2015
0 Communities
1 Members
0 Resources
32 MeSH Terms
The 31-cM region of chromosome 11 including the obesity gene tubby and ATP-sensitive potassium channel genes, SUR1 and Kir6.2, does not contain a major susceptibility locus for NIDDM in 127 non-Hispanic white affected sibships.
Lindner T, Gragnoli C, Schulze J, Rietzsch H, Petzold C, Schröder HE, Cox NJ, Bell GI
(1997) Diabetes 46: 1227-9
MeSH Terms: ATP-Binding Cassette Transporters, Aged, Base Sequence, Chicago, Chromosomes, Human, Pair 11, Diabetes Mellitus, Type 2, Family, Genetic Linkage, Genetic Markers, Genotype, Germany, Humans, Middle Aged, Obesity, Potassium Channels, Potassium Channels, Inwardly Rectifying, Receptors, Drug, Sulfonylurea Receptors, Whites
Added February 22, 2016
0 Communities
1 Members
0 Resources
19 MeSH Terms
Linkage studies in NIDDM with markers near the sulphonylurea receptor gene.
Stirling B, Cox NJ, Bell GI, Hanis CL, Spielman RS, Concannon P
(1995) Diabetologia 38: 1479-81
MeSH Terms: ATP-Binding Cassette Transporters, Alleles, DNA Primers, DNA, Satellite, Diabetes Mellitus, Type 2, Gene Frequency, Genetic Linkage, Genetic Markers, Humans, Islets of Langerhans, Mexican Americans, Molecular Sequence Data, Nuclear Family, Potassium Channels, Potassium Channels, Inwardly Rectifying, Receptors, Drug, Reference Values, Sulfonylurea Compounds, Sulfonylurea Receptors, Texas
Added February 22, 2016
0 Communities
1 Members
0 Resources
20 MeSH Terms
Identification of microsatellite markers near the human genes encoding the beta-cell ATP-sensitive K+ channel and linkage studies with NIDDM in Japanese.
Iwasaki N, Kawamura M, Yamagata K, Cox NJ, Karibe S, Ohgawara H, Inagaki N, Seino S, Bell GI, Omori Y
(1996) Diabetes 45: 267-9
MeSH Terms: ATP-Binding Cassette Transporters, Adenosine Triphosphate, Base Sequence, Chromosomes, Artificial, Yeast, DNA Primers, Diabetes Mellitus, Type 2, Genetic Markers, Humans, Ion Channel Gating, Japan, Microsatellite Repeats, Molecular Sequence Data, Potassium Channels, Potassium Channels, Inwardly Rectifying, Receptors, Drug, Sulfonylurea Receptors
Added February 22, 2016
0 Communities
1 Members
0 Resources
16 MeSH Terms