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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 41 to 50 of 50

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G1 delay in cells overexpressing prostaglandin endoperoxide synthase-2.
DuBois RN, Shao J, Tsujii M, Sheng H, Beauchamp RD
(1996) Cancer Res 56: 733-7
MeSH Terms: Adenoma, Animals, Anti-Inflammatory Agents, Non-Steroidal, Anticarcinogenic Agents, Aspirin, Cell Line, Colonic Neoplasms, Colorectal Neoplasms, Cyclin D1, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinases, Cyclins, DNA, Epithelium, G1 Phase, Humans, Intestines, Kinetics, Oncogene Proteins, Open Reading Frames, Prostaglandin-Endoperoxide Synthases, Proto-Oncogene Proteins, Rats, Recombinant Proteins, Retinoblastoma Protein, Time Factors, Transfection, United States
Added June 14, 2013
1 Communities
1 Members
0 Resources
28 MeSH Terms
Prostaglandin A2 blocks the activation of G1 phase cyclin-dependent kinase without altering mitogen-activated protein kinase stimulation.
Hitomi M, Shu J, Strom D, Hiebert SW, Harter ML, Stacey DW
(1996) J Biol Chem 271: 9376-83
MeSH Terms: 3T3 Cells, Animals, Calcium-Calmodulin-Dependent Protein Kinases, Cell Cycle, Cell Transformation, Neoplastic, Cyclin-Dependent Kinases, Enzyme Activation, G1 Phase, G2 Phase, Kinetics, Mice, Microinjections, Mitosis, Oncogene Proteins v-raf, Oncogenes, Phosphorylation, Prostaglandins A, Retinoblastoma Protein, Retroviridae Proteins, Oncogenic, Time Factors, ras Proteins
Added June 10, 2010
1 Communities
1 Members
0 Resources
21 MeSH Terms
Regions of the retinoblastoma gene product required for its interaction with the E2F transcription factor are necessary for E2 promoter repression and pRb-mediated growth suppression.
Hiebert SW
(1993) Mol Cell Biol 13: 3384-91
MeSH Terms: Adenovirus E1A Proteins, Adenovirus E2 Proteins, Binding Sites, Carrier Proteins, Cell Cycle, Cell Cycle Proteins, Cell Division, DNA-Binding Proteins, E2F Transcription Factors, Female, G1 Phase, Genes, Retinoblastoma, Humans, Promoter Regions, Genetic, Retinoblastoma Protein, Retinoblastoma-Binding Protein 1, Transcription Factor DP1, Transcription Factors, Transfection, Tumor Cells, Cultured, Uterine Cervical Neoplasms
Added June 10, 2010
1 Communities
1 Members
0 Resources
21 MeSH Terms
Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4.
Kato J, Matsushime H, Hiebert SW, Ewen ME, Sherr CJ
(1993) Genes Dev 7: 331-42
MeSH Terms: Adenosine Triphosphate, Animals, Baculoviridae, Cell Line, Cyclin D1, Cyclins, G1 Phase, Genes, Retinoblastoma, Humans, Insecta, Oncogene Proteins, Phosphorylation, Recombinant Fusion Proteins, Retinoblastoma Protein, Transfection
Added June 10, 2010
1 Communities
1 Members
0 Resources
15 MeSH Terms
Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage.
Kessis TD, Slebos RJ, Nelson WG, Kastan MB, Plunkett BS, Han SM, Lorincz AT, Hedrick L, Cho KR
(1993) Proc Natl Acad Sci U S A 90: 3988-92
MeSH Terms: Cell Cycle, Cells, Cultured, Cervix Uteri, DNA Damage, DNA Replication, DNA, Viral, Dactinomycin, Epithelial Cells, Epithelium, Female, G1 Phase, Genes, p53, HeLa Cells, Humans, Keratinocytes, Male, Oncogene Proteins, Viral, Open Reading Frames, Papillomaviridae, Polymerase Chain Reaction, RNA, Messenger, RNA, Viral, Repressor Proteins, Restriction Mapping, Transfection, Tumor Cells, Cultured, Tumor Suppressor Protein p53, Uterine Cervical Neoplasms
Added March 5, 2014
0 Communities
1 Members
0 Resources
28 MeSH Terms
Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage.
Slichenmyer WJ, Nelson WG, Slebos RJ, Kastan MB
(1993) Cancer Res 53: 4164-8
MeSH Terms: Camptothecin, Cell Survival, DNA Damage, G1 Phase, Genes, p53, Humans, Mutation, Radiation Tolerance, Tumor Cells, Cultured
Added March 5, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Apoptosis in erythroid progenitors deprived of erythropoietin occurs during the G1 and S phases of the cell cycle without growth arrest or stabilization of wild-type p53.
Kelley LL, Green WF, Hicks GG, Bondurant MC, Koury MJ, Ruley HE
(1994) Mol Cell Biol 14: 4183-92
MeSH Terms: Animals, Apoptosis, Cell Cycle, Cell Division, Cell Line, Cells, Cultured, DNA, DNA Damage, Erythropoietin, Flow Cytometry, Friend murine leukemia virus, G1 Phase, Genes, p53, Hematopoietic Stem Cells, Kinetics, Mice, Mice, Inbred Strains, Protein Conformation, S Phase, Thymidine, Time Factors, Tumor Suppressor Protein p53
Added May 29, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
Transforming growth factor beta and cell cycle regulation.
Alexandrow MG, Moses HL
(1995) Cancer Res 55: 1452-7
MeSH Terms: Cell Cycle, Cyclin-Dependent Kinases, Cyclins, G1 Phase, Genes, myc, RNA, Messenger, S Phase, Signal Transduction, Transforming Growth Factor beta
Added February 17, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Transforming growth factor beta 1 inhibits mouse keratinocytes late in G1 independent of effects on gene transcription.
Alexandrow MG, Moses HL
(1995) Cancer Res 55: 3928-32
MeSH Terms: Animals, Aphidicolin, Dichlororibofuranosylbenzimidazole, G1 Phase, Keratinocytes, Mice, Mice, Inbred BALB C, Mimosine, RNA Polymerase II, S Phase, Transcription, Genetic, Transforming Growth Factor beta
Added February 17, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Downregulation of JE and KC genes by glucocorticoids does not prevent the G0----G1 transition in BALB/3T3 cells.
Rameh LE, Armelin MC
(1992) Mol Cell Biol 12: 4612-21
MeSH Terms: 3T3 Cells, Animals, Antigens, Polyomavirus Transforming, Base Sequence, Blotting, Northern, Chemokine CCL2, Chemokine CXCL1, Chemokines, Chemokines, CXC, Chemotactic Factors, Cycloheximide, Cytokines, DNA, Dexamethasone, Down-Regulation, G1 Phase, Gene Expression Regulation, Glucocorticoids, Hydrocortisone, Kinetics, Mice, Molecular Sequence Data, Proto-Oncogene Proteins c-jun, Resting Phase, Cell Cycle
Added November 26, 2018
0 Communities
1 Members
0 Resources
MeSH Terms