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Mutational analysis of ligand binding activity of beta 2 adrenergic receptor expressed in Escherichia coli.
Breyer RM, Strosberg AD, Guillet JG
(1990) EMBO J 9: 2679-84
MeSH Terms: Amino Acid Sequence, Escherichia coli, Humans, Iodocyanopindolol, Kinetics, Ligands, Molecular Sequence Data, Mutation, Oligonucleotide Probes, Pindolol, Plasmids, Receptors, Adrenergic, beta, Recombinant Proteins, Restriction Mapping
Added December 21, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms
NMR methods for determining the structures of enzyme/inhibitor complexes as an aid in drug design.
Fesik SW, Zuiderweg ER, Olejniczak ET, Gampe RT
(1990) Biochem Pharmacol 40: 161-7
MeSH Terms: Drug Design, Enzyme Inhibitors, Ligands, Magnetic Resonance Spectroscopy, Pepsin A
Added March 5, 2014
0 Communities
1 Members
0 Resources
5 MeSH Terms
Opioid signal transduction in intact and fragmented SH-SY5Y neural cells.
Carter BD, Medzihradsky F
(1992) J Neurochem 58: 1611-9
MeSH Terms: Endorphins, Enkephalin, Ala(2)-MePhe(4)-Gly(5)-, Enkephalins, Guanosine Triphosphate, Humans, Intracellular Membranes, Ligands, Nervous System Neoplasms, Signal Transduction, Tumor Cells, Cultured
Added March 5, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Functional expression of the human serotonin 5-HT1A receptor in Escherichia coli. Ligand binding properties and interaction with recombinant G protein alpha-subunits.
Bertin B, Freissmuth M, Breyer RM, Schütz W, Strosberg AD, Marullo S
(1992) J Biol Chem 267: 8200-6
MeSH Terms: 8-Hydroxy-2-(di-n-propylamino)tetralin, Amino Acid Sequence, Binding, Competitive, Electrophoresis, Polyacrylamide Gel, Escherichia coli, GTP-Binding Proteins, Gene Expression, Guanosine 5'-O-(3-Thiotriphosphate), Humans, Ligands, Molecular Sequence Data, Plasmids, Receptors, Serotonin, Recombinant Proteins, Signal Transduction, Tetrahydronaphthalenes
Added December 21, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
Conformation of two non-immunosuppressive FK506 analogs when bound to FKBP by isotope-filtered NMR.
Petros AM, Kawai M, Luly JR, Fesik SW
(1992) FEBS Lett 308: 309-14
MeSH Terms: Binding Sites, Calcineurin, Calmodulin-Binding Proteins, Carbon Isotopes, Carrier Proteins, Ligands, Magnetic Resonance Spectroscopy, Models, Molecular, Molecular Conformation, Phosphoprotein Phosphatases, Protons, Tacrolimus, Tacrolimus Binding Proteins
Added March 5, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Phosphofructokinase. II. Role of ligands in pH-dependent structural changes of the rabbit muscle enzyme.
Bock PE, Frieden C
(1976) J Biol Chem 251: 5637-43
MeSH Terms: Adenosine Triphosphate, Animals, Binding Sites, Enzyme Activation, Hydrogen-Ion Concentration, Inosine Nucleotides, Kinetics, Ligands, Magnesium, Muscles, Phosphofructokinase-1, Protein Binding, Protein Conformation, Rabbits
Added January 20, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms