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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 31 to 40 of 148

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Pathway analyses identify TGFBR2 as potential breast cancer susceptibility gene: results from a consortium study among Asians.
Ma X, Beeghly-Fadiel A, Lu W, Shi J, Xiang YB, Cai Q, Shen H, Shen CY, Ren Z, Matsuo K, Khoo US, Iwasaki M, Long J, Zhang B, Ji BT, Zheng Y, Wang W, Hu Z, Liu Y, Wu PE, Shieh YL, Wang S, Xie X, Ito H, Kasuga Y, Chan KY, Iwata H, Tsugane S, Gao YT, Shu XO, Moses HL, Zheng W
(2012) Cancer Epidemiol Biomarkers Prev 21: 1176-84
MeSH Terms: Adult, Breast, Breast Neoplasms, Case-Control Studies, China, Female, Genetic Predisposition to Disease, Humans, Middle Aged, Polymerase Chain Reaction, Polymorphism, Restriction Fragment Length, Polymorphism, Single Nucleotide, Prognosis, Protein Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Risk Factors, Signal Transduction
Added February 17, 2014
1 Communities
5 Members
0 Resources
18 MeSH Terms
TGF-β receptor II loss promotes mammary carcinoma progression by Th17 dependent mechanisms.
Novitskiy SV, Pickup MW, Gorska AE, Owens P, Chytil A, Aakre M, Wu H, Shyr Y, Moses HL
(2011) Cancer Discov 1: 430-41
MeSH Terms: Animals, Breast Neoplasms, Cell Line, Tumor, Chemokines, CXC, Cyclooxygenase 2, Disease Progression, Female, Gene Expression Regulation, Neoplastic, Humans, Interleukin-17, Ligands, Mammary Neoplasms, Experimental, Mice, Mice, Inbred C57BL, Mice, Knockout, Monocytes, Neoplasm Metastasis, Protein Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Signal Transduction, Th17 Cells, Transcriptome, alpha-Fetoproteins
Added February 17, 2014
2 Communities
3 Members
0 Resources
24 MeSH Terms
Loss of TGF-β responsiveness in prostate stromal cells alters chemokine levels and facilitates the development of mixed osteoblastic/osteolytic bone lesions.
Li X, Sterling JA, Fan KH, Vessella RL, Shyr Y, Hayward SW, Matrisian LM, Bhowmick NA
(2012) Mol Cancer Res 10: 494-503
MeSH Terms: Animals, Bone Neoplasms, Cell Line, Tumor, Cell Transformation, Neoplastic, Chemokines, Fibroblasts, Humans, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, SCID, Osteoblasts, Prostatic Neoplasms, Protein Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Stromal Cells, Transforming Growth Factor beta
Added December 10, 2013
0 Communities
3 Members
0 Resources
19 MeSH Terms
BMP2 signals loss of epithelial character in epicardial cells but requires the Type III TGFβ receptor to promote invasion.
Hill CR, Sanchez NS, Love JD, Arrieta JA, Hong CC, Brown CB, Austin AF, Barnett JV
(2012) Cell Signal 24: 1012-22
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Bone Morphogenetic Protein 2, Carrier Proteins, Cell Differentiation, Cell Movement, Cells, Cultured, Coronary Vessels, Epithelial Cells, Epithelial-Mesenchymal Transition, Mice, Mice, Knockout, Myocytes, Smooth Muscle, Neuropeptides, Pericardium, Proteoglycans, Receptors, Transforming Growth Factor beta, Smad Proteins, Transforming Growth Factors
Added August 19, 2012
1 Communities
3 Members
0 Resources
19 MeSH Terms
Transforming growth factor-β protein inversely regulates in vivo differentiation of interleukin-17 (IL-17)-producing CD4+ and CD8+ T cells.
Dwivedi VP, Tousif S, Bhattacharya D, Prasad DV, Van Kaer L, Das J, Das G
(2012) J Biol Chem 287: 2943-7
MeSH Terms: Animals, CD8-Positive T-Lymphocytes, Cell Differentiation, Lymphocyte Depletion, Mice, Mice, Knockout, Receptors, Transforming Growth Factor beta, Th17 Cells, Transforming Growth Factor beta
Added March 20, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
TGFβ and BMP-2 regulate epicardial cell invasion via TGFβR3 activation of the Par6/Smurf1/RhoA pathway.
Sánchez NS, Barnett JV
(2012) Cell Signal 24: 539-548
MeSH Terms: Adaptor Proteins, Signal Transducing, Adenoviridae, Animals, Bone Morphogenetic Protein 2, Cell Communication, Cell Differentiation, Cell Line, Cell Movement, Coronary Vessels, Epithelial Cells, Epithelial-Mesenchymal Transition, Gene Expression, Mice, Mice, Knockout, Pericardium, Proteoglycans, RNA, Small Interfering, Receptors, Transforming Growth Factor beta, Signal Transduction, Transfection, Transforming Growth Factor beta2, Ubiquitin-Protein Ligases, rhoA GTP-Binding Protein
Added January 10, 2014
1 Communities
1 Members
0 Resources
23 MeSH Terms
Transforming growth factor beta signaling in adult cardiovascular diseases and repair.
Doetschman T, Barnett JV, Runyan RB, Camenisch TD, Heimark RL, Granzier HL, Conway SJ, Azhar M
(2012) Cell Tissue Res 347: 203-23
MeSH Terms: Aging, Angiotensin II, Animals, Cardiac Rehabilitation, Cardiovascular Diseases, Epithelial-Mesenchymal Transition, Gene Expression, Genetic Variation, Humans, Mitogen-Activated Protein Kinases, Mutation, Receptors, Transforming Growth Factor beta, Signal Transduction, Smad Proteins, Transforming Growth Factor beta
Added February 21, 2016
0 Communities
1 Members
0 Resources
15 MeSH Terms
Endocardial cell epithelial-mesenchymal transformation requires Type III TGFβ receptor interaction with GIPC.
Townsend TA, Robinson JY, How T, DeLaughter DM, Blobe GC, Barnett JV
(2012) Cell Signal 24: 247-56
MeSH Terms: Activin Receptors, Adaptor Proteins, Signal Transducing, Amino Acid Sequence, Animals, Bone Morphogenetic Protein 2, Chick Embryo, Endocardial Cushions, Epithelial Cells, Epithelial-Mesenchymal Transition, Green Fluorescent Proteins, Molecular Sequence Data, Protein Interaction Domains and Motifs, Proteoglycans, Receptors, Transforming Growth Factor beta, Recombinant Proteins, Tissue Culture Techniques, Transforming Growth Factor beta2
Added February 21, 2016
0 Communities
1 Members
0 Resources
17 MeSH Terms
Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma.
Ijichi H, Chytil A, Gorska AE, Aakre ME, Bierie B, Tada M, Mohri D, Miyabayashi K, Asaoka Y, Maeda S, Ikenoue T, Tateishi K, Wright CV, Koike K, Omata M, Moses HL
(2011) J Clin Invest 121: 4106-17
MeSH Terms: Animals, Carcinoma, Pancreatic Ductal, Chemokines, CXC, Connective Tissue Growth Factor, Female, Gene Expression, Humans, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Nude, Pancreatic Neoplasms, Protein Serine-Threonine Kinases, Proto-Oncogene Proteins p21(ras), Receptor, Transforming Growth Factor-beta Type II, Receptors, Interleukin-8B, Receptors, Transforming Growth Factor beta, Signal Transduction, Stromal Cells, Tumor Microenvironment
Added March 10, 2014
3 Communities
2 Members
0 Resources
20 MeSH Terms
The cytoplasmic domain of TGFβR3 through its interaction with the scaffolding protein, GIPC, directs epicardial cell behavior.
Sánchez NS, Hill CR, Love JD, Soslow JH, Craig E, Austin AF, Brown CB, Czirok A, Camenisch TD, Barnett JV
(2011) Dev Biol 358: 331-43
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Base Sequence, Carrier Proteins, Cell Differentiation, Cell Movement, Cell Proliferation, Coronary Vessel Anomalies, DNA Primers, Epithelial-Mesenchymal Transition, Female, Gene Expression Regulation, Developmental, Gene Knockdown Techniques, Mice, Mice, 129 Strain, Mice, Inbred C57BL, Mice, Knockout, Models, Cardiovascular, Myocytes, Smooth Muscle, Neuropeptides, Pericardium, Pregnancy, Protein Interaction Domains and Motifs, Proteoglycans, Receptors, Transforming Growth Factor beta, Signal Transduction, Time-Lapse Imaging, Transforming Growth Factor beta1, Transforming Growth Factor beta2
Added January 10, 2014
1 Communities
2 Members
0 Resources
29 MeSH Terms