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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 31 to 40 of 48

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A monomeric, biologically active, full-length human apolipoprotein E.
Zhang Y, Vasudevan S, Sojitrawala R, Zhao W, Cui C, Xu C, Fan D, Newhouse Y, Balestra R, Jerome WG, Weisgraber K, Li Q, Wang J
(2007) Biochemistry 46: 10722-32
MeSH Terms: Apolipoprotein E3, Circular Dichroism, Dimyristoylphosphatidylcholine, Humans, Lipid Metabolism, Lipoproteins, HDL, Magnetic Resonance Spectroscopy, Mutant Proteins, Protein Binding, Protein Engineering, Protein Structure, Tertiary, Receptors, LDL, Structure-Activity Relationship, Thermodynamics
Added December 10, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms
Inducible Cre/loxP recombination in the mouse proximal tubule.
Dworniczak B, Skryabin B, Tchinda J, Heuck S, Seesing FJ, Metzger D, Chambon P, Horst J, Pennekamp P
(2007) Nephron Exp Nephrol 106: e11-20
MeSH Terms: Animals, Cells, Cultured, Integrases, Kidney Tubules, Proximal, Mice, Mice, Transgenic, Protein Engineering, Recombinant Fusion Proteins, Tamoxifen
Added September 9, 2013
0 Communities
0 Members
1 Resources
9 MeSH Terms
New algorithms and an in silico benchmark for computational enzyme design.
Zanghellini A, Jiang L, Wollacott AM, Cheng G, Meiler J, Althoff EA, Röthlisberger D, Baker D
(2006) Protein Sci 15: 2785-94
MeSH Terms: Algorithms, Animals, Bacillus, Binding Sites, Carboxy-Lyases, Cattle, Computational Biology, Crystallography, Enzyme Activation, Enzymes, Escherichia coli, Fructose-Bisphosphate Aldolase, Models, Molecular, Plant Viruses, Protein Conformation, Protein Engineering, Saccharomyces cerevisiae
Added January 24, 2015
1 Communities
1 Members
0 Resources
17 MeSH Terms
A monomeric human apolipoprotein E carboxyl-terminal domain.
Fan D, Li Q, Korando L, Jerome WG, Wang J
(2004) Biochemistry 43: 5055-64
MeSH Terms: Amino Acid Sequence, Apolipoproteins E, Circular Dichroism, Conserved Sequence, Cross-Linking Reagents, Dimyristoylphosphatidylcholine, Escherichia coli, Guanidine, Humans, Hydrophobic and Hydrophilic Interactions, Lipoproteins, HDL, Models, Molecular, Molecular Sequence Data, Mutation, Nuclear Magnetic Resonance, Biomolecular, Protein Denaturation, Protein Engineering, Protein Structure, Secondary, Protein Structure, Tertiary, Recombinant Proteins, Sequence Homology, Amino Acid, Solubility
Added December 10, 2013
0 Communities
1 Members
0 Resources
22 MeSH Terms
A protein knockdown strategy to study the function of beta-catenin in tumorigenesis.
Cong F, Zhang J, Pao W, Zhou P, Varmus H
(2003) BMC Mol Biol 4: 10
MeSH Terms: Animals, Cell Division, Cell Line, Tumor, Colorectal Neoplasms, Cytoskeletal Proteins, Mice, Mice, Nude, Protein Engineering, Proto-Oncogene Proteins, Recombinant Fusion Proteins, Signal Transduction, Trans-Activators, Ubiquitins, Wnt Proteins, Zebrafish Proteins, beta Catenin
Added March 24, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Collagen stabilization at atomic level: crystal structure of designed (GlyProPro)10foldon.
Stetefeld J, Frank S, Jenny M, Schulthess T, Kammerer RA, Boudko S, Landwehr R, Okuyama K, Engel J
(2003) Structure 11: 339-46
MeSH Terms: Animals, Collagen, Crystallography, X-Ray, Humans, Peptides, Polymers, Protein Engineering, Protein Structure, Tertiary
Added November 2, 2017
0 Communities
1 Members
0 Resources
8 MeSH Terms
Engineering and design of ligand-induced conformational change in proteins.
Mizoue LS, Chazin WJ
(2002) Curr Opin Struct Biol 12: 459-63
MeSH Terms: Calbindins, Calmodulin, Carrier Proteins, Integrins, Ligands, Maltose-Binding Proteins, Models, Molecular, Protein Binding, Protein Conformation, Protein Engineering, Proteins, S100 Calcium Binding Protein G
Added December 10, 2013
0 Communities
1 Members
0 Resources
12 MeSH Terms
Protein engineering of protein kinase A catalytic subunits results in the acquisition of novel inhibitor sensitivity.
Niswender CM, Ishihara RW, Judge LM, Zhang C, Shokat KM, McKnight GS
(2002) J Biol Chem 277: 28916-22
MeSH Terms: Alanine, Amino Acid Sequence, Animals, Catalysis, Catalytic Domain, Cyclic AMP-Dependent Protein Kinases, Dose-Response Relationship, Drug, Enzyme Inhibitors, Glycine, Humans, Inhibitory Concentration 50, Isoleucine, Isoquinolines, Leucine, Lysine, Methionine, Mice, Models, Chemical, Models, Molecular, Molecular Sequence Data, Mutation, Plasmids, Protein Engineering, Protein Isoforms, Protein Structure, Tertiary, Signal Transduction, Sulfonamides, Transcription, Genetic, Transfection, Tumor Cells, Cultured
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies.
Petros AM, Nettesheim DG, Wang Y, Olejniczak ET, Meadows RP, Mack J, Swift K, Matayoshi ED, Zhang H, Thompson CB, Fesik SW
(2000) Protein Sci 9: 2528-34
MeSH Terms: Amino Acid Sequence, Apoptosis, Binding Sites, Carrier Proteins, Humans, Models, Molecular, Mutagenesis, Site-Directed, Nuclear Magnetic Resonance, Biomolecular, Peptides, Protein Binding, Protein Engineering, Protein Structure, Secondary, Protein Structure, Tertiary, Proto-Oncogene Proteins c-bcl-2, Structure-Activity Relationship, bcl-Associated Death Protein, bcl-X Protein
Added March 5, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Creation of a stress-activated p90 ribosomal S6 kinase. The carboxyl-terminal tail of the MAPK-activated protein kinases dictates the signal transduction pathway in which they function.
Smith JA, Poteet-Smith CE, Lannigan DA, Freed TA, Zoltoski AJ, Sturgill TW
(2000) J Biol Chem 275: 31588-93
MeSH Terms: Amino Acid Sequence, Animals, Binding Sites, Cell Line, Cricetinae, Enzyme Activation, Humans, MAP Kinase Signaling System, Mitogen-Activated Protein Kinase Kinases, Mitogen-Activated Protein Kinases, Molecular Sequence Data, Phosphorylation, Precipitin Tests, Protein Engineering, Protein Structure, Tertiary, Rats, Receptors, Estrogen, Recombinant Fusion Proteins, Ribosomal Protein S6 Kinases, Substrate Specificity, Transfection, p38 Mitogen-Activated Protein Kinases
Added January 20, 2015
0 Communities
1 Members
0 Resources
22 MeSH Terms