Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 31 to 34 of 34

Publication Record

Connections

Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation.
Hong F, Sekhar KR, Freeman ML, Liebler DC
(2005) J Biol Chem 280: 31768-75
MeSH Terms: Biotin, Cell Cycle Proteins, Cell Line, Cullin Proteins, Cysteine, DNA-Binding Proteins, Electrophoresis, Polyacrylamide Gel, Humans, Intracellular Signaling Peptides and Proteins, Kelch-Like ECH-Associated Protein 1, Mass Spectrometry, NF-E2-Related Factor 2, Peptides, Proteins, Trans-Activators, Transfection, Ubiquitin
Added March 5, 2014
0 Communities
2 Members
0 Resources
17 MeSH Terms
Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2.
Sekhar KR, Yan XX, Freeman ML
(2002) Oncogene 21: 6829-34
MeSH Terms: Animals, Antioxidants, Cysteine Endopeptidases, DNA-Binding Proteins, Half-Life, Humans, Intracellular Signaling Peptides and Proteins, Kelch-Like ECH-Associated Protein 1, Mice, Multienzyme Complexes, NF-E2-Related Factor 2, Proteasome Endopeptidase Complex, Proteins, Response Elements, Trans-Activators, Ubiquitin
Added March 5, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase.
Sekhar KR, Spitz DR, Harris S, Nguyen TT, Meredith MJ, Holt JT, Gius D, Marnett LJ, Summar ML, Freeman ML, Guis D
(2002) Free Radic Biol Med 32: 650-62
MeSH Terms: Anti-Inflammatory Agents, Non-Steroidal, Blotting, Northern, Carcinoma, Hepatocellular, Carrier Proteins, Chloramphenicol O-Acetyltransferase, DNA-Binding Proteins, Fluorescent Antibody Technique, Indirect, Glutamate-Cysteine Ligase, Glutathione, Humans, Ibuprofen, Indomethacin, Leucine Zippers, Liver Neoplasms, MAP Kinase Kinase 1, Mitogen-Activated Protein Kinase Kinases, NF-E2-Related Factor 2, Oxidation-Reduction, Promoter Regions, Genetic, Protein-Serine-Threonine Kinases, RNA, Messenger, Trans-Activators, Transfection, Tumor Cells, Cultured
Added March 5, 2014
0 Communities
2 Members
0 Resources
24 MeSH Terms
Inhibition of the 26S proteasome induces expression of GLCLC, the catalytic subunit for gamma-glutamylcysteine synthetase.
Sekhar KR, Soltaninassab SR, Borrelli MJ, Xu ZQ, Meredith MJ, Domann FE, Freeman ML
(2000) Biochem Biophys Res Commun 270: 311-7
MeSH Terms: Acetylcysteine, Azetidines, Cells, Cultured, DNA-Binding Proteins, Enzyme Induction, Glutamate-Cysteine Ligase, Glutathione, Liver, NF-E2-Related Factor 2, Neoplasm Proteins, Peptide Hydrolases, Proteasome Endopeptidase Complex, Protein Structure, Quaternary, Response Elements, Trans-Activators
Added March 5, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms