Dnt1 acts as a mitotic inhibitor of the spindle checkpoint protein dma1 in fission yeast.
Wang Y, Li WZ, Johnson AE, Luo ZQ, Sun XL, Feoktistova A, McDonald WH, McLeod I, Yates JR, Gould KL, McCollum D, Jin QW
(2012) Mol Biol Cell 23
: 3348-56MeSH Terms: Cell Cycle Checkpoints, Cell Cycle Proteins, Cell Division, Cytokinesis, Microtubule-Associated Proteins, Mitosis, Mutation, Nuclear Proteins, Protein Binding, Protein Serine-Threonine Kinases, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Spindle Apparatus, UbiquitinationAdded March 5, 2014
14 MeSH Terms
Engrailed is required in maturing serotonin neurons to regulate the cytoarchitecture and survival of the dorsal raphe nucleus.
Fox SR, Deneris ES
(2012) J Neurosci 32
: 7832-42MeSH Terms: Alleles, Animals, Animals, Newborn, Cell Count, Cell Death, Cell Survival, Chromatography, High Pressure Liquid, Fluorescent Antibody Technique, Homeodomain Proteins, Immunohistochemistry, Mice, Mice, Knockout, Mitosis, Nerve Tissue Proteins, Neurons, RNA, Raphe Nuclei, Real-Time Polymerase Chain Reaction, SerotoninAdded April 17, 2013
19 MeSH Terms
Fission yeast Dma1 requires RING domain dimerization for its ubiquitin ligase activity and mitotic checkpoint function.
Johnson AE, Collier SE, Ohi MD, Gould KL
(2012) J Biol Chem 287
: 25741-8MeSH Terms: Amino Acid Sequence, Cell Cycle Proteins, Conserved Sequence, M Phase Cell Cycle Checkpoints, Mitosis, Molecular Sequence Data, Protein Multimerization, Protein Structure, Quaternary, Protein Transport, RING Finger Domains, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Sequence Homology, Amino Acid, Spindle Apparatus, Ubiquitin-Protein LigasesAdded March 5, 2014
15 MeSH Terms
Multisite phosphoregulation of Cdc25 activity refines the mitotic entrance and exit switches.
Lu LX, Domingo-Sananes MR, Huzarska M, Novak B, Gould KL
(2012) Proc Natl Acad Sci U S A 109
: 9899-904MeSH Terms: Animals, CDC2 Protein Kinase, Cell Cycle, Enzyme Activation, Humans, Mitosis, Phosphorylation, Xenopus, cdc25 PhosphatasesAdded March 5, 2014
9 MeSH Terms
The fission yeast septation initiation network (SIN) kinase, Sid2, is required for SIN asymmetry and regulates the SIN scaffold, Cdc11.
Feoktistova A, Morrell-Falvey J, Chen JS, Singh NS, Balasubramanian MK, Gould KL
(2012) Mol Biol Cell 23
: 1636-45MeSH Terms: Anaphase, Cell Cycle Proteins, Mitosis, Phosphorylation, Protein Kinases, Protein Processing, Post-Translational, Protein Serine-Threonine Kinases, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Signal TransductionAdded December 5, 2013
10 MeSH Terms
Cdk1 phosphorylation of the kinetochore protein Nsk1 prevents error-prone chromosome segregation.
Chen JS, Lu LX, Ohi MD, Creamer KM, English C, Partridge JF, Ohi R, Gould KL
(2011) J Cell Biol 195
: 583-93MeSH Terms: CDC2 Protein Kinase, Cell Cycle Proteins, Chromosome Segregation, Chromosomes, Fungal, Dyneins, Kinetochores, Microtubules, Mitosis, Phosphorylation, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Spindle ApparatusAdded March 5, 2014
12 MeSH Terms
MiR-15 family regulates postnatal mitotic arrest of cardiomyocytes.
Porrello ER, Johnson BA, Aurora AB, Simpson E, Nam YJ, Matkovich SJ, Dorn GW, van Rooij E, Olson EN
(2011) Circ Res 109
: 670-9MeSH Terms: Animals, Animals, Newborn, Cell Cycle, Gene Expression Profiling, Mice, Mice, Inbred C57BL, Mice, Transgenic, MicroRNAs, Mitosis, Multigene Family, Myocytes, CardiacAdded August 1, 2014
11 MeSH Terms
Proper regulation of Cdc42 activity is required for tight actin concentration at the equator during cytokinesis in adherent mammalian cells.
Zhu X, Wang J, Moriguchi K, Liow LT, Ahmed S, Kaverina I, Murata-Hori M
(2011) Exp Cell Res 317
: 2384-9MeSH Terms: Actin Cytoskeleton, Actins, Animals, Cell Line, Cell Shape, Cytokinesis, Epithelial Cells, Kidney, Microscopy, Phase-Contrast, Mitosis, RNA, Small Interfering, Rats, Recombinant Fusion Proteins, Time-Lapse Imaging, Transfection, cdc42 GTP-Binding Protein, rhoA GTP-Binding ProteinAdded December 10, 2013
17 MeSH Terms
State of the APC/C: organization, function, and structure.
McLean JR, Chaix D, Ohi MD, Gould KL
(2011) Crit Rev Biochem Mol Biol 46
: 118-36MeSH Terms: Anaphase-Promoting Complex-Cyclosome, Animals, Catalysis, Cell Cycle Proteins, Cell Nucleus, Humans, Meiosis, Microscopy, Electron, Mitosis, Models, Biological, Spindle Apparatus, Ubiquitin-Protein Ligase Complexes, Ubiquitin-Protein LigasesAdded March 5, 2014
13 MeSH Terms
Tumor necrosis factor alpha inhibits olfactory regeneration in a transgenic model of chronic rhinosinusitis-associated olfactory loss.
Turner JH, Liang KL, May L, Lane AP
(2010) Am J Rhinol Allergy 24
: 336-40MeSH Terms: Animals, Chronic Disease, Disease Models, Animal, Mice, Mice, Transgenic, Mitosis, Neurogenesis, Olfaction Disorders, Olfactory Bulb, Olfactory Mucosa, Rhinitis, Sinusitis, Tumor Necrosis Factor-alphaAdded July 23, 2020