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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 31 to 40 of 215

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Enhancing integrin α1 inserted (I) domain affinity to ligand potentiates integrin α1β1-mediated down-regulation of collagen synthesis.
Shi M, Pedchenko V, Greer BH, Van Horn WD, Santoro SA, Sanders CR, Hudson BG, Eichman BF, Zent R, Pozzi A
(2012) J Biol Chem 287: 35139-35152
MeSH Terms: Amino Acid Substitution, Animals, Cell Line, Transformed, Collagen Type IV, Down-Regulation, Enzyme Activation, Extracellular Signal-Regulated MAP Kinases, Humans, Integrin alpha1beta1, Laminin, Ligands, MAP Kinase Signaling System, Mice, Mice, Mutant Strains, Models, Molecular, Mutation, Missense, Nuclear Magnetic Resonance, Biomolecular, Protein Binding, Protein Biosynthesis, Protein Structure, Tertiary
Added February 24, 2014
1 Communities
6 Members
1 Resources
20 MeSH Terms
Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice.
Xiao S, Brooks CR, Zhu C, Wu C, Sweere JM, Petecka S, Yeste A, Quintana FJ, Ichimura T, Sobel RA, Bonventre JV, Kuchroo VK
(2012) Proc Natl Acad Sci U S A 109: 12105-10
MeSH Terms: Animals, Autoantibodies, Autoimmunity, B-Lymphocytes, Regulatory, Blotting, Western, Crosses, Genetic, DNA Primers, Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Hepatitis A Virus Cellular Receptor 1, Interferon-gamma, Interleukin-10, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Mutant Strains, Mucins, Mutagenesis, Protein Structure, Tertiary, Reverse Transcriptase Polymerase Chain Reaction, T-Lymphocytes
Added September 12, 2016
1 Communities
1 Members
0 Resources
21 MeSH Terms
The continuing evolution of the Langendorff and ejecting murine heart: new advances in cardiac phenotyping.
Liao R, Podesser BK, Lim CC
(2012) Am J Physiol Heart Circ Physiol 303: H156-67
MeSH Terms: Animals, Anura, Cardiac Electrophysiology, Heart, History, 19th Century, History, 20th Century, History, 21st Century, Humans, Mice, Mice, Mutant Strains, Myocardial Contraction, Perfusion, Stroke Volume, Tissue and Organ Harvesting
Added February 19, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Haploinsufficiency of the E3 ubiquitin ligase C-terminus of heat shock cognate 70 interacting protein (CHIP) produces specific behavioral impairments.
McLaughlin B, Buendia MA, Saborido TP, Palubinsky AM, Stankowski JN, Stanwood GD
(2012) PLoS One 7: e36340
MeSH Terms: Animals, Anxiety, Behavior, Animal, Emotions, Haploinsufficiency, Male, Maze Learning, Mice, Mice, Mutant Strains, Motivation, Motor Activity, Motor Skills, Ubiquitin-Protein Ligases
Added August 14, 2014
1 Communities
3 Members
0 Resources
13 MeSH Terms
Integrin α1/Akita double-knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy.
Yu L, Su Y, Paueksakon P, Cheng H, Chen X, Wang H, Harris RC, Zent R, Pozzi A
(2012) Kidney Int 81: 1086-97
MeSH Terms: Age Factors, Animals, Blood Glucose, Diabetes Mellitus, Type 1, Diabetic Nephropathies, Disease Models, Animal, Fibrosis, Genetic Predisposition to Disease, Glomerular Filtration Rate, Glomerulonephritis, Humans, Insulin, Integrin alpha1, Kidney Glomerulus, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Knockout, Mice, Mutant Strains, Mutation, Phenotype, Sclerosis, Severity of Illness Index
Added February 24, 2014
1 Communities
4 Members
1 Resources
23 MeSH Terms
Molecule-specific imaging and quantitation of A2E in the RPE.
Ablonczy Z, Gutierrez DB, Grey AC, Schey KL, Crouch RK
(2012) Adv Exp Med Biol 723: 75-81
MeSH Terms: ATP-Binding Cassette Transporters, Animals, Carrier Proteins, Disease Models, Animal, Eye Proteins, Lipofuscin, Macular Degeneration, Mice, Mice, Inbred C57BL, Mice, Mutant Strains, Oxidation-Reduction, Pyridinium Compounds, Retinal Pigment Epithelium, Retinoids, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Stargardt Disease, cis-trans-Isomerases
Added May 27, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Overexpression of angiopoietin-2 impairs myocardial angiogenesis and exacerbates cardiac fibrosis in the diabetic db/db mouse model.
Chen JX, Zeng H, Reese J, Aschner JL, Meyrick B
(2012) Am J Physiol Heart Circ Physiol 302: H1003-12
MeSH Terms: Angiopoietin-2, Animals, Apoptosis, Caspase 3, Cells, Cultured, Coronary Vessels, Diabetes Mellitus, Disease Models, Animal, Endothelium, Vascular, Fibrosis, Intercellular Adhesion Molecule-1, Male, Mice, Mice, Mutant Strains, Myocardium, Neovascularization, Pathologic, Proto-Oncogene Proteins, Receptor, TIE-2, Up-Regulation, Vascular Cell Adhesion Molecule-1, Vascular Endothelial Growth Factor A, Wnt Proteins
Added May 26, 2015
0 Communities
1 Members
0 Resources
22 MeSH Terms
Lysine392, a K63-linked ubiquitination site in NEMO, mediates inflammatory osteoclastogenesis and osteolysis.
Alhawagri M, Yamanaka Y, Ballard D, Oltz E, Abu-Amer Y
(2012) J Orthop Res 30: 554-60
MeSH Terms: Animals, Bone Resorption, Extracellular Signal-Regulated MAP Kinases, Germ-Line Mutation, I-kappa B Proteins, Intracellular Signaling Peptides and Proteins, JNK Mitogen-Activated Protein Kinases, Lysine, Mice, Mice, Mutant Strains, Mutagenesis, Site-Directed, Osteitis, Osteoclasts, Osteolysis, Polymethyl Methacrylate, Prosthesis Failure, Signal Transduction, Ubiquitination, p38 Mitogen-Activated Protein Kinases
Added January 10, 2014
1 Communities
0 Members
0 Resources
19 MeSH Terms
Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways.
Tsuboi K, Okamoto Y, Ikematsu N, Inoue M, Shimizu Y, Uyama T, Wang J, Deutsch DG, Burns MP, Ulloa NM, Tokumura A, Ueda N
(2011) Biochim Biophys Acta 1811: 565-77
MeSH Terms: Animals, Arachidonic Acids, Brain, COS Cells, Chlorocebus aethiops, Endocannabinoids, Ethanolamines, Male, Mice, Mice, Mutant Strains, Models, Biological, Oleic Acids, Phospholipase D, Plasmalogens, Polyunsaturated Alkamides, Signal Transduction
Added April 10, 2014
0 Communities
0 Members
1 Resources
16 MeSH Terms
Early alveolar epithelial dysfunction promotes lung inflammation in a mouse model of Hermansky-Pudlak syndrome.
Atochina-Vasserman EN, Bates SR, Zhang P, Abramova H, Zhang Z, Gonzales L, Tao JQ, Gochuico BR, Gahl W, Guo CJ, Gow AJ, Beers MF, Guttentag S
(2011) Am J Respir Crit Care Med 184: 449-58
MeSH Terms: Aging, Animals, Cell Movement, Chemokine CCL2, Chemotactic Factors, Cytokines, Disease Models, Animal, Fibrosis, Hermanski-Pudlak Syndrome, Humans, Lung, Macrophages, Mice, Mice, Inbred C57BL, Mice, Mutant Strains, Nitroso Compounds, Phospholipids, Pneumonia, Pulmonary Alveoli, Pulmonary Surfactant-Associated Protein D, Respiratory Mucosa, Severity of Illness Index, Time Factors
Added January 20, 2015
0 Communities
1 Members
0 Resources
23 MeSH Terms