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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 31 to 40 of 47

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Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas.
Crawford HC, Scoggins CR, Washington MK, Matrisian LM, Leach SD
(2002) J Clin Invest 109: 1437-44
MeSH Terms: Animals, Apoptosis, Fas Ligand Protein, Immunohistochemistry, Matrix Metalloproteinase 7, Membrane Glycoproteins, Metaplasia, Mice, Mice, Transgenic, Pancreas, Pancreatic Neoplasms, Protein Precursors, Proto-Oncogene Proteins c-bcl-2, Signal Transduction, Transforming Growth Factor alpha
Added March 5, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Matrilysin [MMP-7] expression selects for cells with reduced sensitivity to apoptosis.
Fingleton B, Vargo-Gogola T, Crawford HC, Matrisian LM
(2001) Neoplasia 3: 459-68
MeSH Terms: Animals, Antibodies, Monoclonal, Apoptosis, Breast, Clone Cells, Concanavalin A, Cycloheximide, DNA, Complementary, Enzyme Induction, Enzyme Inhibitors, Epithelial Cells, Fas Ligand Protein, Female, Humans, Interleukin-2, Killer Cells, Natural, Lymphocyte Activation, Male, Mammary Glands, Animal, Matrix Metalloproteinase 7, Membrane Glycoproteins, Mice, Mitomycin, Protein Synthesis Inhibitors, Rabbits, Rats, Recombinant Fusion Proteins, Spleen, Staurosporine, T-Lymphocytes, Transfection, fas Receptor
Added March 5, 2014
1 Communities
1 Members
0 Resources
32 MeSH Terms
Pro-collagenase-1 (matrix metalloproteinase-1) binds the alpha(2)beta(1) integrin upon release from keratinocytes migrating on type I collagen.
Dumin JA, Dickeson SK, Stricker TP, Bhattacharyya-Pakrasi M, Roby JD, Santoro SA, Parks WC
(2001) J Biol Chem 276: 29368-74
MeSH Terms: Adult, Binding Sites, Blood Platelets, Cell Movement, Cells, Cultured, Collagen, Collagenases, Enzyme Precursors, Humans, In Situ Hybridization, Integrins, Keratinocytes, Matrix Metalloproteinase 1, Matrix Metalloproteinase 3, Matrix Metalloproteinase 7, Matrix Metalloproteinase 9, Platelet Adhesiveness, Receptors, Collagen, Skin, Transcription, Genetic, U937 Cells
Added March 5, 2014
1 Communities
2 Members
0 Resources
21 MeSH Terms
The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors.
Crawford HC, Fingleton B, Gustavson MD, Kurpios N, Wagenaar RA, Hassell JA, Matrisian LM
(2001) Mol Cell Biol 21: 1370-83
MeSH Terms: Animals, Base Sequence, Binding Sites, Colonic Neoplasms, Cytoskeletal Proteins, DNA Primers, DNA-Binding Proteins, Genes, Reporter, Humans, Intestinal Neoplasms, Luciferases, Lymphoid Enhancer-Binding Factor 1, Matrix Metalloproteinase 7, Mice, Mutagenesis, Site-Directed, Promoter Regions, Genetic, Proto-Oncogene Proteins c-jun, Trans-Activators, Transcription Factors, Transcriptional Activation, Tumor Cells, Cultured, beta Catenin
Added March 5, 2014
1 Communities
1 Members
0 Resources
22 MeSH Terms
Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1.
Noë V, Fingleton B, Jacobs K, Crawford HC, Vermeulen S, Steelant W, Bruyneel E, Matrisian LM, Mareel M
(2001) J Cell Sci 114: 111-118
MeSH Terms: Animals, Cadherins, Cell Line, Cell Membrane, Dogs, Humans, Matrix Metalloproteinase 3, Matrix Metalloproteinase 7, Tumor Cells, Cultured
Added March 5, 2014
1 Communities
1 Members
0 Resources
9 MeSH Terms
Matrix metalloproteinase-7-dependent release of tumor necrosis factor-alpha in a model of herniated disc resorption.
Haro H, Crawford HC, Fingleton B, Shinomiya K, Spengler DM, Matrisian LM
(2000) J Clin Invest 105: 143-50
MeSH Terms: Animals, Bone Resorption, Cell Migration Inhibition, Cells, Cultured, Coculture Techniques, Diffusion Chambers, Culture, Disease Models, Animal, Enzyme Induction, Intervertebral Disc, Intervertebral Disc Displacement, Macrophages, Peritoneal, Matrix Metalloproteinase 3, Matrix Metalloproteinase 7, Mice, Mice, Inbred Strains, Mice, Knockout, Tumor Necrosis Factor-alpha
Added March 5, 2014
1 Communities
1 Members
0 Resources
17 MeSH Terms
Matrix metalloproteinase-3-dependent generation of a macrophage chemoattractant in a model of herniated disc resorption.
Haro H, Crawford HC, Fingleton B, MacDougall JR, Shinomiya K, Spengler DM, Matrisian LM
(2000) J Clin Invest 105: 133-41
MeSH Terms: Animals, Blotting, Western, Cell Migration Inhibition, Chondrocytes, Coculture Techniques, Culture Media, Conditioned, Diffusion Chambers, Culture, Disease Models, Animal, Dose-Response Relationship, Drug, Intervertebral Disc, Intervertebral Disc Displacement, Macrophages, Peritoneal, Matrix Metalloproteinase 3, Matrix Metalloproteinase 7, Mice, Mice, Inbred Strains, Mice, Knockout, Organ Culture Techniques, RNA, Messenger, Rats, Reverse Transcriptase Polymerase Chain Reaction, Tumor Necrosis Factor-alpha, Up-Regulation
Added March 5, 2014
1 Communities
1 Members
0 Resources
23 MeSH Terms
The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis.
Powell WC, Fingleton B, Wilson CL, Boothby M, Matrisian LM
(1999) Curr Biol 9: 1441-7
MeSH Terms: Animals, Apoptosis, Epithelial Cells, Fas Ligand Protein, Immunohistochemistry, Male, Matrix Metalloproteinase 7, Membrane Glycoproteins, Mice, Mice, Inbred C57BL, Mice, Knockout, Orchiectomy, Prostate, Substrate Specificity, fas Receptor
Added December 10, 2013
1 Communities
2 Members
0 Resources
15 MeSH Terms
Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense.
Wilson CL, Ouellette AJ, Satchell DP, Ayabe T, López-Boado YS, Stratman JL, Hultgren SJ, Matrisian LM, Parks WC
(1999) Science 286: 113-7
MeSH Terms: Amino Acid Sequence, Animals, Catalysis, Cytoplasmic Granules, Escherichia coli, Escherichia coli Infections, Female, Humans, Immunity, Innate, Immunity, Mucosal, Intestinal Mucosa, Intestine, Small, Male, Matrix Metalloproteinase 7, Metalloendopeptidases, Mice, Molecular Sequence Data, Paneth Cells, Protein Precursors, Recombinant Fusion Proteins, Salmonella typhimurium, Tissue Extracts
Added August 13, 2010
1 Communities
0 Members
0 Resources
22 MeSH Terms
The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors.
Crawford HC, Fingleton BM, Rudolph-Owen LA, Goss KJ, Rubinfeld B, Polakis P, Matrisian LM
(1999) Oncogene 18: 2883-91
MeSH Terms: Adenoma, Animals, Base Sequence, Cytoskeletal Proteins, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Intestinal Neoplasms, Lymphoid Enhancer-Binding Factor 1, Matrix Metalloproteinase 7, Metalloendopeptidases, Mice, Mice, Inbred C57BL, Molecular Sequence Data, Promoter Regions, Genetic, Signal Transduction, Trans-Activators, Transcription Factors, Transcriptional Activation, beta Catenin
Added March 5, 2014
1 Communities
1 Members
0 Resources
19 MeSH Terms