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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 31 to 38 of 38

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Oxidation of benzo[a]pyrene by recombinant human cytochrome P450 enzymes.
Bauer E, Guo Z, Ueng YF, Bell LC, Zeldin D, Guengerich FP
(1995) Chem Res Toxicol 8: 136-42
MeSH Terms: Benzo(a)pyrene, Benzoflavones, Biotransformation, Cytochrome P-450 Enzyme System, Humans, Oxidation-Reduction, Recombinant Proteins
Added March 5, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms
Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver.
Shimada T, Guengerich FP
(1989) Proc Natl Acad Sci U S A 86: 462-5
MeSH Terms: Aflatoxin B1, Aflatoxins, Antibodies, Benzoflavones, Biotransformation, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme System, Humans, Immunochemistry, Microsomes, Liver, Mixed Function Oxygenases, Nifedipine, Oxidation-Reduction, Sterigmatocystin, Troleandomycin
Added March 5, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Activation of amino-alpha-carboline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a copper phthalocyanine cellulose extract of cigarette smoke condensate by cytochrome P-450 enzymes in rat and human liver microsomes.
Shimada T, Guengerich FP
(1991) Cancer Res 51: 5284-91
MeSH Terms: Aflatoxin B1, Animals, Aroclors, Benzoflavones, Carbolines, Chlorodiphenyl (54% Chlorine), Cytochrome P-450 Enzyme System, DNA, Dose-Response Relationship, Drug, Humans, Imidazoles, In Vitro Techniques, Male, Microsomes, Liver, Mutagens, Plants, Toxic, Quinidine, Rats, Rats, Inbred Strains, SOS Response, Genetics, Safrole, Smoke, Tobacco, beta-Galactosidase
Added March 5, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
Contributions of human liver cytochrome P450 enzymes to the N-oxidation of 4,4'-methylene-bis(2-chloroaniline).
Yun CH, Shimada T, Guengerich FP
(1992) Carcinogenesis 13: 217-22
MeSH Terms: Benzoflavones, Cytochrome P-450 Enzyme System, Humans, Methylenebis(chloroaniline), Microsomes, Liver, Oxidation-Reduction, Recombinant Proteins
Added March 5, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms
Human liver microsomal N-hydroxylation of dapsone by cytochrome P-4503A4.
Fleming CM, Branch RA, Wilkinson GR, Guengerich FP
(1992) Mol Pharmacol 41: 975-80
MeSH Terms: Antibodies, Benzoflavones, Cytochrome P-450 Enzyme System, Humans, Hydroxylation, Isoenzymes, Kinetics, Microsomes, Liver, Norpregnenes, Troleandomycin
Added March 5, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Roles of human liver cytochrome P4502C and 3A enzymes in the 3-hydroxylation of benzo(a)pyrene.
Yun CH, Shimada T, Guengerich FP
(1992) Cancer Res 52: 1868-74
MeSH Terms: Antibodies, Benzo(a)pyrene, Benzoflavones, Cytochrome P-450 Enzyme System, Gene Expression, Humans, Hydroxylation, Isoenzymes, Kinetics, Liver, Microsomes, Liver, Norpregnenes, Recombinant Proteins, Saccharomyces cerevisiae, Sulfaphenazole
Added March 5, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Beta-naphthoflavone induction of a cytochrome P-450 arachidonic acid epoxygenase in chick embryo liver distinct from the aryl hydrocarbon hydroxylase and from phenobarbital-induced arachidonate epoxygenase.
Nakai K, Ward AM, Gannon M, Rifkind AB
(1992) J Biol Chem 267: 19503-12
MeSH Terms: Amino Acid Sequence, Animals, Arachidonic Acid, Aryl Hydrocarbon Hydroxylases, Benzoflavones, Chick Embryo, Cytochrome P-450 CYP2J2, Cytochrome P-450 Enzyme System, Cytochromes b5, Enzyme Induction, Liver, Microsomes, Liver, Mixed Function Oxygenases, Molecular Sequence Data, Oxygenases, Phenobarbital, Polychlorinated Dibenzodioxins, beta-Naphthoflavone
Added January 6, 2014
1 Communities
1 Members
0 Resources
18 MeSH Terms
Identification of the pharmacogenetic determinants of alfentanil metabolism: cytochrome P-450 3A4. An explanation of the variable elimination clearance.
Yun CH, Wood M, Wood AJ, Guengerich FP
(1992) Anesthesiology 77: 467-74
MeSH Terms: Alfentanil, Benzoflavones, Cytochrome P-450 Enzyme System, Drug Interactions, Fentanyl, Humans, Microsomes, Liver
Added March 5, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms