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Results: 31 to 40 of 50

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Successful translation of pharmacogenetics into the clinic: the abacavir example.
Phillips E, Mallal S
(2009) Mol Diagn Ther 13: 1-9
MeSH Terms: Anti-HIV Agents, Dideoxynucleosides, Drug Hypersensitivity, Genetic Predisposition to Disease, Genetic Testing, HIV Infections, HLA-B Antigens, Humans, Patch Tests, Pharmacogenetics, Syndrome
Added March 30, 2020
0 Communities
1 Members
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MeSH Terms
Refining abacavir hypersensitivity diagnoses using a structured clinical assessment and genetic testing in the Swiss HIV Cohort Study.
Rauch A, Nolan D, Thurnheer C, Fux CA, Cavassini M, Chave JP, Opravil M, Phillips E, Mallal S, Furrer H, Swiss HIV Cohort Study
(2008) Antivir Ther 13: 1019-28
MeSH Terms: Anti-HIV Agents, Cohort Studies, Dideoxynucleosides, Drug Hypersensitivity, Genetic Predisposition to Disease, Genetic Variation, HIV Infections, HLA-B Antigens, Humans, Patch Tests, Switzerland
Added March 30, 2020
0 Communities
1 Members
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MeSH Terms
A review of drug patch testing and implications for HIV clinicians.
Shear NH, Milpied B, Bruynzeel DP, Phillips EJ
(2008) AIDS 22: 999-1007
MeSH Terms: Anti-HIV Agents, Dideoxynucleosides, Drug Hypersensitivity, HIV Infections, Humans, Nevirapine, Patch Tests
Added March 30, 2020
0 Communities
1 Members
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MeSH Terms
Cytokine profiling in abacavir hypersensitivity patients.
Almeida CA, Martin AM, Nolan D, Lucas A, Cameron PU, James I, Phillips E, Mallal S
(2008) Antivir Ther 13: 281-8
MeSH Terms: Anti-HIV Agents, Cells, Cultured, Cytokines, Dideoxynucleosides, Drug Hypersensitivity, HIV Infections, HLA-B Antigens, Humans, Interferon-gamma, Leukocytes, Mononuclear, Reverse Transcriptase Inhibitors
Added March 30, 2020
0 Communities
1 Members
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MeSH Terms
High sensitivity of human leukocyte antigen-b*5701 as a marker for immunologically confirmed abacavir hypersensitivity in white and black patients.
Saag M, Balu R, Phillips E, Brachman P, Martorell C, Burman W, Stancil B, Mosteller M, Brothers C, Wannamaker P, Hughes A, Sutherland-Phillips D, Mallal S, Shaefer M, Study of Hypersensitivity to Abacavir and Pharmacogenetic Evaluation Study Team
(2008) Clin Infect Dis 46: 1111-8
MeSH Terms: Adolescent, Adult, Aged, Anti-HIV Agents, Blacks, Dideoxynucleosides, Drug Hypersensitivity, Female, Gene Frequency, HLA-B Antigens, Humans, Male, Middle Aged, Pharmacogenetics, Sensitivity and Specificity, Skin Tests, United States, Whites
Added March 30, 2020
0 Communities
1 Members
0 Resources
18 MeSH Terms
HLA-B*5701 screening for hypersensitivity to abacavir.
Mallal S, Phillips E, Carosi G, Molina JM, Workman C, Tomazic J, J├Ągel-Guedes E, Rugina S, Kozyrev O, Cid JF, Hay P, Nolan D, Hughes S, Hughes A, Ryan S, Fitch N, Thorborn D, Benbow A, PREDICT-1 Study Team
(2008) N Engl J Med 358: 568-79
MeSH Terms: Adolescent, Adult, Aged, Dideoxynucleosides, Double-Blind Method, Drug Hypersensitivity, Female, Genetic Markers, Genetic Testing, Genotype, HIV Infections, HIV-1, HLA-B Antigens, Humans, Male, Middle Aged, Patch Tests, Reverse Transcriptase Inhibitors
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
External quality assessment of HLA-B*5701 reporting: an international multicentre survey.
Hammond E, Almeida CA, Mamotte C, Nolan D, Phillips E, Schollaardt TA, Gill MJ, Angel JB, Neurath D, Li J, Giulivi T, McIntyre C, Koultchitski G, Wong B, Reis M, Rachlis A, Cole DE, Chew CB, Neifer S, Lalonde R, Roger M, Jeanneau A, Mallal S
(2007) Antivir Ther 12: 1027-32
MeSH Terms: Alleles, Anti-HIV Agents, DNA Primers, DNA Probes, HLA, Dideoxynucleosides, Drug Hypersensitivity, Genetic Testing, HLA-B Antigens, Humans, Polymerase Chain Reaction, Quality Control, Reproducibility of Results, Sensitivity and Specificity
Added March 30, 2020
0 Communities
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MeSH Terms
Drug hypersensitivity in HIV.
Phillips E, Mallal S
(2007) Curr Opin Allergy Clin Immunol 7: 324-30
MeSH Terms: AIDS-Related Opportunistic Infections, Anti-HIV Agents, Anti-Infective Agents, Dideoxynucleosides, Drug Hypersensitivity, Genetic Predisposition to Disease, HIV Infections, HLA-B Antigens, Humans, Reverse Transcriptase Inhibitors, Trimethoprim, Sulfamethoxazole Drug Combination
Added March 30, 2020
0 Communities
1 Members
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MeSH Terms
Immune responses to abacavir in antigen-presenting cells from hypersensitive patients.
Martin AM, Almeida CA, Cameron P, Purcell AW, Nolan D, James I, McCluskey J, Phillips E, Landay A, Mallal S
(2007) AIDS 21: 1233-44
MeSH Terms: Antigen-Presenting Cells, CD40 Antigens, Cells, Cultured, Dideoxynucleosides, Drug Hypersensitivity, Endoplasmic Reticulum, Endosomes, Fluorescent Antibody Technique, HIV Seropositivity, HLA-B Antigens, HSP70 Heat-Shock Proteins, Histocompatibility Antigens Class I, Humans, Immunophenotyping, Interferon-gamma, Microscopy, Confocal, Monocytes, Receptors, Cell Surface, Reverse Transcriptase Inhibitors
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
A simple screening approach to reduce B*5701-associated abacavir hypersensitivity on the basis of sequence variation in HIV reverse transcriptase.
Chui CK, Brumme ZL, Brumme CJ, Yip B, Phillips EJ, Montaner JS, Harrigan PR
(2007) Clin Infect Dis 44: 1503-8
MeSH Terms: Adult, Alleles, Anti-HIV Agents, Antiretroviral Therapy, Highly Active, Contraindications, Dideoxynucleosides, Drug Hypersensitivity, Female, Genetic Testing, Genotype, HIV Reverse Transcriptase, HLA-B Antigens, Humans, Male, Mutation, Prevalence, Reverse Transcriptase Inhibitors, Sensitivity and Specificity, Sequence Analysis, RNA
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms