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Metabolic regulation of CaMKII protein and caspases in Xenopus laevis egg extracts.
McCoy F, Darbandi R, Chen SI, Eckard L, Dodd K, Jones K, Baucum AJ, Gibbons JA, Lin SH, Colbran RJ, Nutt LK
(2013) J Biol Chem 288: 8838-48
MeSH Terms: Animals, Apoptosis, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Caspase 2, Caspase 3, Caspase 7, Cell Death, Cell Proliferation, Gene Expression Regulation, Developmental, Gene Expression Regulation, Enzymologic, Mass Spectrometry, Oocytes, Oxygen, Peptides, Phosphorylation, Protein Phosphatase 1, Recombinant Proteins, Sepharose, Serine, Xenopus, Xenopus laevis
Added June 21, 2013
0 Communities
1 Members
0 Resources
21 MeSH Terms
Calmodulin mutations associated with recurrent cardiac arrest in infants.
Crotti L, Johnson CN, Graf E, De Ferrari GM, Cuneo BF, Ovadia M, Papagiannis J, Feldkamp MD, Rathi SG, Kunic JD, Pedrazzini M, Wieland T, Lichtner P, Beckmann BM, Clark T, Shaffer C, Benson DW, Kääb S, Meitinger T, Strom TM, Chazin WJ, Schwartz PJ, George AL
(2013) Circulation 127: 1009-17
MeSH Terms: Amino Acid Sequence, Calcium Signaling, Calmodulin, Child, Preschool, Cohort Studies, Female, Follow-Up Studies, Genetic Association Studies, Heart Arrest, Humans, Infant, Infant, Newborn, Long QT Syndrome, Male, Molecular Sequence Data, Mutation, Pedigree, Recurrence
Added March 12, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
NMR studies of the interaction of calmodulin with IQ motif peptides.
Damo SM, Feldkamp MD, Chagot B, Chazin WJ
(2013) Methods Mol Biol 963: 173-86
MeSH Terms: Amino Acid Motifs, Apoproteins, Calcium, Calmodulin, Humans, Intracellular Space, NAV1.5 Voltage-Gated Sodium Channel, Nuclear Magnetic Resonance, Biomolecular, Peptide Fragments, Protein Binding, Signal Transduction
Added March 7, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Differential association of postsynaptic signaling protein complexes in striatum and hippocampus.
Baucum AJ, Brown AM, Colbran RJ
(2013) J Neurochem 124: 490-501
MeSH Terms: Animals, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Corpus Striatum, Hippocampus, Immunoprecipitation, Male, Mice, Mice, Inbred C57BL, Microfilament Proteins, Myosins, Nerve Tissue Proteins, Phosphorylation, Protein Phosphatase 1, Receptors, Glutamate, Receptors, N-Methyl-D-Aspartate, Signal Transduction, Subcellular Fractions, Synapses, Vesicular Transport Proteins
Added June 21, 2013
0 Communities
3 Members
0 Resources
19 MeSH Terms
Functional regulation of ClC-3 in the migration of vascular smooth muscle cells.
Ganapathi SB, Wei SG, Zaremba A, Lamb FS, Shears SB
(2013) Hypertension 61: 174-9
MeSH Terms: Animals, Aorta, Benzylamines, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Cell Movement, Cells, Cultured, Chloride Channels, Inositol Phosphates, Mice, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, Niflumic Acid, Protein Kinase Inhibitors, Signal Transduction, Sulfonamides
Added February 22, 2016
0 Communities
1 Members
0 Resources
15 MeSH Terms
Genetic inhibition of CaMKII in dorsal striatal medium spiny neurons reduces functional excitatory synapses and enhances intrinsic excitability.
Klug JR, Mathur BN, Kash TL, Wang HD, Matthews RT, Robison AJ, Anderson ME, Deutch AY, Lovinger DM, Colbran RJ, Winder DG
(2012) PLoS One 7: e45323
MeSH Terms: Animals, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Corpus Striatum, Excitatory Postsynaptic Potentials, Female, Male, Mice, Mice, Transgenic, Neurons, Peptides, Receptors, AMPA, Synaptic Transmission
Added March 7, 2014
0 Communities
4 Members
0 Resources
12 MeSH Terms
Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1.
Martínez-López N, García-Rodríguez JL, Varela-Rey M, Gutiérrez V, Fernández-Ramos D, Beraza N, Aransay AM, Schlangen K, Lozano JJ, Aspichueta P, Luka Z, Wagner C, Evert M, Calvisi DF, Lu SC, Mato JM, Martínez-Chantar ML
(2012) Gastroenterology 143: 787-798.e13
MeSH Terms: AMP-Activated Protein Kinases, Animals, Apoptosis, Azacitidine, Calcium-Calmodulin-Dependent Protein Kinase Kinase, Carcinoma, Hepatocellular, Cell Line, Tumor, Cell Proliferation, Cell Transformation, Neoplastic, Cyclic AMP-Dependent Protein Kinases, DNA Methylation, Enzyme Activation, Enzyme Inhibitors, Glycine N-Methyltransferase, Guanine Nucleotide Exchange Factors, Humans, Liver Neoplasms, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Nude, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase Kinases, Phosphorylation, Protein Serine-Threonine Kinases, RNA Interference, Ribosomal Protein S6 Kinases, 90-kDa, Signal Transduction, Time Factors, Transfection, Tumor Burden, ras Guanine Nucleotide Exchange Factors, ras Proteins
Added January 20, 2015
0 Communities
1 Members
0 Resources
33 MeSH Terms
Genome-wide association of pericardial fat identifies a unique locus for ectopic fat.
Fox CS, White CC, Lohman K, Heard-Costa N, Cohen P, Zhang Y, Johnson AD, Emilsson V, Liu CT, Chen YD, Taylor KD, Allison M, Budoff M, CARDIoGRAM Consortium, Rotter JI, Carr JJ, Hoffmann U, Ding J, Cupples LA, Liu Y
(2012) PLoS Genet 8: e1002705
MeSH Terms: Adipose Tissue, Adult, Animals, Asians, Atherosclerosis, Blacks, Body Fat Distribution, Body Mass Index, Calcium-Calmodulin-Dependent Protein Kinases, Coronary Disease, Female, Gene Expression Regulation, Genome-Wide Association Study, Hispanic or Latino, Humans, Intra-Abdominal Fat, Intracellular Signaling Peptides and Proteins, Male, Mice, Middle Aged, Obesity, Pericardium, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Tomography, X-Ray Computed, Whites
Added February 15, 2014
0 Communities
1 Members
0 Resources
26 MeSH Terms
Attention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation.
Sakrikar D, Mazei-Robison MS, Mergy MA, Richtand NW, Han Q, Hamilton PJ, Bowton E, Galli A, Veenstra-Vanderweele J, Gill M, Blakely RD
(2012) J Neurosci 32: 5385-97
MeSH Terms: Adolescent, Amphetamine, Analysis of Variance, Attention Deficit Disorder with Hyperactivity, Bacterial Proteins, Benzylamines, Biotinylation, Calcium, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Cell Line, Transformed, Child, Child, Preschool, Cholera Toxin, Cohort Studies, Dopamine, Dopamine Plasma Membrane Transport Proteins, Dopamine Uptake Inhibitors, Dose-Response Relationship, Drug, Electrochemistry, Female, Humans, Immunoprecipitation, Luminescent Proteins, Male, Membrane Microdomains, Membrane Proteins, Piperazines, Polymorphism, Single Nucleotide, Protein Kinase Inhibitors, Protein Transport, Sulfonamides, Transfection, Tritium
Added December 5, 2013
3 Communities
2 Members
0 Resources
33 MeSH Terms
Substrate-selective and calcium-independent activation of CaMKII by α-actinin.
Jalan-Sakrikar N, Bartlett RK, Baucum AJ, Colbran RJ
(2012) J Biol Chem 287: 15275-83
MeSH Terms: Actinin, Actins, Amino Acid Sequence, Animals, Binding Sites, Calcium, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Enzyme Activation, HEK293 Cells, Humans, Immunoblotting, Mice, Microscopy, Fluorescence, Models, Molecular, Molecular Sequence Data, Mutation, Phosphorylation, Prosencephalon, Protein Binding, Protein Structure, Tertiary, Receptors, N-Methyl-D-Aspartate, Sequence Homology, Amino Acid, Serine, Substrate Specificity, Threonine
Added December 5, 2013
2 Communities
2 Members
0 Resources
25 MeSH Terms