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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 31 to 40 of 78

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Hereditary spastic paraplegia-causing mutations in atlastin-1 interfere with BMPRII trafficking.
Zhao J, Hedera P
(2013) Mol Cell Neurosci 52: 87-96
MeSH Terms: Animals, Blotting, Western, Bone Morphogenetic Protein Receptors, Type II, COS Cells, Cells, Cultured, Chlorocebus aethiops, Flow Cytometry, GTP-Binding Proteins, HEK293 Cells, Humans, Immunohistochemistry, Immunoprecipitation, Membrane Proteins, Microscopy, Confocal, Mutagenesis, Site-Directed, Mutation, Neurons, Protein Transport, Rats, Spastic Paraplegia, Hereditary, Transfection
Added December 5, 2013
1 Communities
0 Members
0 Resources
21 MeSH Terms
BMP4 is a novel paracrine inhibitor of liver regeneration.
Do N, Zhao R, Ray K, Ho K, Dib M, Ren X, Kuzontkoski P, Terwilliger E, Karp SJ
(2012) Am J Physiol Gastrointest Liver Physiol 303: G1220-7
MeSH Terms: Animals, Bone Morphogenetic Protein 4, Bone Morphogenetic Protein Receptors, Type I, Dependovirus, Hep G2 Cells, Hepatectomy, Humans, Liver Regeneration, Mice, Smad1 Protein
Added May 22, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
A potential role for insulin resistance in experimental pulmonary hypertension.
West J, Niswender KD, Johnson JA, Pugh ME, Gleaves L, Fessel JP, Hemnes AR
(2013) Eur Respir J 41: 861-71
MeSH Terms: Animals, Body Composition, Bone Morphogenetic Protein Receptors, Type II, Cell Line, Dexamethasone, Diet, High-Fat, Disease Models, Animal, Energy Metabolism, Humans, Hypertension, Pulmonary, Insulin Resistance, Male, Mice, Mice, Transgenic, Mutation, Phenotype, Protein Transport, Rats, Receptors, Glucocorticoid
Added May 20, 2014
0 Communities
3 Members
0 Resources
19 MeSH Terms
Longitudinal analysis casts doubt on the presence of genetic anticipation in heritable pulmonary arterial hypertension.
Larkin EK, Newman JH, Austin ED, Hemnes AR, Wheeler L, Robbins IM, West JD, Phillips JA, Hamid R, Loyd JE
(2012) Am J Respir Crit Care Med 186: 892-6
MeSH Terms: Adult, Age of Onset, Aged, Anticipation, Genetic, Bone Morphogenetic Protein Receptors, Type II, Familial Primary Pulmonary Hypertension, Female, Humans, Hypertension, Pulmonary, Kaplan-Meier Estimate, Male, Middle Aged, Mutation, Pedigree, Registries
Added March 5, 2014
0 Communities
6 Members
0 Resources
15 MeSH Terms
Role of BMPR2 alternative splicing in heritable pulmonary arterial hypertension penetrance.
Cogan J, Austin E, Hedges L, Womack B, West J, Loyd J, Hamid R
(2012) Circulation 126: 1907-16
MeSH Terms: Adult, Aged, Alternative Splicing, Bone Morphogenetic Protein Receptors, Type II, Familial Primary Pulmonary Hypertension, Female, Humans, Hypertension, Pulmonary, Male, Middle Aged, Penetrance, Protein Isoforms
Added March 27, 2014
0 Communities
3 Members
0 Resources
12 MeSH Terms
Pre-implantation genetic testing for hereditary pulmonary arterial hypertension: promise and caution.
Hamid R, Loyd J
(2012) Eur Respir J 39: 1292-3
MeSH Terms: Bone Morphogenetic Protein Receptors, Type II, Familial Primary Pulmonary Hypertension, Female, Humans, Hypertension, Pulmonary, Male, Mutation, Preimplantation Diagnosis
Added March 27, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance.
Flynn C, Zheng S, Yan L, Hedges L, Womack B, Fessel J, Cogan J, Austin E, Loyd J, West J, Zhao Z, Hamid R
(2012) Am J Respir Cell Mol Biol 47: 20-7
MeSH Terms: Aged, Bone Morphogenetic Protein Receptors, Type II, Cell Cycle, Familial Primary Pulmonary Hypertension, Female, Gene Expression Profiling, Gene Expression Regulation, Humans, Hypertension, Pulmonary, Lung, Lymphocytes, Male, Mutation, Penetrance, Reactive Oxygen Species, Signal Transduction
Added December 10, 2013
0 Communities
6 Members
0 Resources
16 MeSH Terms
Cytoskeletal defects in Bmpr2-associated pulmonary arterial hypertension.
Johnson JA, Hemnes AR, Perrien DS, Schuster M, Robinson LJ, Gladson S, Loibner H, Bai S, Blackwell TR, Tada Y, Harral JW, Talati M, Lane KB, Fagan KA, West J
(2012) Am J Physiol Lung Cell Mol Physiol 302: L474-84
MeSH Terms: Amino Acid Substitution, Angiotensin-Converting Enzyme 2, Animals, Blood Pressure, Bone Morphogenetic Protein Receptors, Type II, Cells, Cultured, Cytoskeleton, Endothelial Cells, Enzyme Activation, Familial Primary Pulmonary Hypertension, Female, Gene Expression Profiling, Heart Ventricles, Humans, Hypertension, Pulmonary, Lung, Male, Mice, Mice, Transgenic, Microvessels, Neuropeptides, Oligonucleotide Array Sequence Analysis, Peptidyl-Dipeptidase A, Phosphorylation, Recombinant Proteins, rac GTP-Binding Proteins, rac1 GTP-Binding Protein
Added April 25, 2013
0 Communities
3 Members
0 Resources
27 MeSH Terms
Physiologic and molecular consequences of endothelial Bmpr2 mutation.
Majka S, Hagen M, Blackwell T, Harral J, Johnson JA, Gendron R, Paradis H, Crona D, Loyd JE, Nozik-Grayck E, Stenmark KR, West J
(2011) Respir Res 12: 84
MeSH Terms: Animals, Apoptosis, Bone Morphogenetic Protein Receptors, Type II, Bone Morphogenetic Proteins, Cell Proliferation, Cells, Cultured, Endothelial Cells, Familial Primary Pulmonary Hypertension, Gene Expression Regulation, Genotype, Hypertension, Pulmonary, Inflammation, Lung, Mice, Mice, Transgenic, Microvessels, Mutation, Phenotype, Promoter Regions, Genetic, Receptor, TIE-2, Signal Transduction, Thrombosis, Ventricular Function, Right, Ventricular Pressure
Added August 20, 2012
0 Communities
3 Members
0 Resources
24 MeSH Terms
Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators.
Owens P, Pickup MW, Novitskiy SV, Chytil A, Gorska AE, Aakre ME, West J, Moses HL
(2012) Proc Natl Acad Sci U S A 109: 2814-9
MeSH Terms: Animals, Antigens, Polyomavirus Transforming, Bone Morphogenetic Protein Receptors, Type II, Cell Movement, Cell Proliferation, Chemokines, Disease Progression, Female, Humans, Inflammation, Mammary Glands, Animal, Mammary Neoplasms, Animal, Mammary Tumor Virus, Mouse, Mice, Myeloid Cells, Neoplasm Invasiveness, Neoplasm Metastasis, Neovascularization, Pathologic, Paracrine Communication, Signal Transduction, Tumor Microenvironment
Added March 7, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms